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Etofibrate

Base Information Edit
  • Chemical Name:Etofibrate
  • CAS No.:31637-97-5
  • Molecular Formula:C18H18ClNO5
  • Molecular Weight:363.798
  • Hs Code.:2942000000
  • European Community (EC) Number:250-743-1
  • UNII:23TF67G79M
  • DSSTox Substance ID:DTXSID80185521
  • Nikkaji Number:J19.853F
  • Wikipedia:Etofibrate
  • Wikidata:Q4116990
  • NCI Thesaurus Code:C65588
  • Metabolomics Workbench ID:152057
  • ChEMBL ID:CHEMBL358150
  • Mol file:31637-97-5.mol
Etofibrate

Synonyms:etofibrate;etofibrate hydrochloride;Lipo-Merz;Tricerol

Suppliers and Price of Etofibrate
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • Etofibrate
  • 50mg
  • $ 100.00
  • TRC
  • Etofibrate
  • 500mg
  • $ 865.00
  • TCI Chemical
  • Etofibrate
  • 50MG
  • $ 174.00
  • TCI Chemical
  • Etofibrate
  • 250MG
  • $ 610.00
  • Sigma-Aldrich
  • Etofibrate analytical standard
  • 25mg
  • $ 97.80
  • DC Chemicals
  • Ethofibrate >98%
  • 250 mg
  • $ 600.00
  • DC Chemicals
  • Ethofibrate >98%
  • 1 g
  • $ 1300.00
  • Crysdot
  • Etofibrate 98%
  • 250mg
  • $ 192.00
  • Crysdot
  • Etofibrate 98%
  • 25mg
  • $ 57.00
  • Crysdot
  • Etofibrate 98%
  • 10mg
  • $ 37.00
Total 68 raw suppliers
Chemical Property of Etofibrate Edit
Chemical Property:
  • Appearance/Colour:White to off-white solid 
  • Vapor Pressure:1.25E-09mmHg at 25°C 
  • Melting Point:42-44 °C 
  • Refractive Index:1.555 
  • Boiling Point:486.8 °C at 760 mmHg 
  • PKA:3.04±0.10(Predicted) 
  • Flash Point:248.2 °C 
  • PSA:74.72000 
  • Density:1.267g/cm3 
  • LogP:3.29260 
  • Storage Temp.:Refrigerator 
  • Solubility.:Chloroform (Slightly), Methanol (Slightly) 
  • Water Solubility.:7.276mg/L(room temperature) 
  • XLogP3:3.5
  • Hydrogen Bond Donor Count:0
  • Hydrogen Bond Acceptor Count:6
  • Rotatable Bond Count:9
  • Exact Mass:363.0873504
  • Heavy Atom Count:25
  • Complexity:449
Purity/Quality:

99% *data from raw suppliers

Etofibrate *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CC(C)(C(=O)OCCOC(=O)C1=CN=CC=C1)OC2=CC=C(C=C2)Cl
  • Description Etofibrate is a combination of niacin and clofibrate that acts as a hypolipidemic agent. In vivo, etofibrate decreases plasma cholesterol and triglyceride concentrations and increases bile cholesterol content in rats. It also decreases thromboxane formation, platelet aggregation, and plasma viscosity and inhibits neointima formation in a carotid artery balloon injury rat model. Formulations containing etofibrate have been used to treat hyperlipidemia.
  • Uses Antilipemic; reducing lipid levels in the blood.
  • Therapeutic Function Antihyperlipidemic
Technology Process of Etofibrate

There total 1 articles about Etofibrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Guidance literature:
Na-β-nicotinat, Cl-CH2CH2-O-C(O)-C(Me)2-O-C6H4-Cl-4, Δ;
Guidance literature:
With hydrogenchloride; [RuCl2(CO)2(Ph2P-3-C6H4COOH)2]; In methanol; water; at 75 ℃; for 0.333333h;
DOI:10.1016/j.saa.2007.11.001
Guidance literature:
With (R)-3,3'-bis(2,4,6-triisopropylphenyl)binol phosphoric acid; [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-N1,N1′]bis{3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-κN]phenyl-κC}iridium(III) hexafluorophosphate; In 1,4-dioxane; for 14h; enantioselective reaction; Irradiation;
DOI:10.1126/science.aar6376
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