1H-Pyrazole-5-carboxylic acid, 3-methoxy-1-phenyl-, methyl ester

Base Information

Chemical Name:1H-Pyrazole-5-carboxylic acid, 3-methoxy-1-phenyl-, methyl ester
CAS No.:92576-30-2
Molecular Formula:C12H12N2O3
Molecular Weight:232.23500
Hs Code.:
DSSTox Substance ID:DTXSID70577193
Wikidata:Q82467136

Synonyms:92576-30-2;1H-Pyrazole-5-carboxylic acid, 3-methoxy-1-phenyl-, methyl ester;methyl 5-methoxy-2-phenylpyrazole-3-carboxylate;SCHEMBL20028706;DTXSID70577193;Methyl 3-methoxy-1-phenyl-1H-pyrazole-5-carboxylate

Suppliers and Price of 1H-Pyrazole-5-carboxylic acid, 3-methoxy-1-phenyl-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1H-Pyrazole-5-carboxylic acid, 3-methoxy-1-phenyl-, methyl ester

Chemical Property:

Melting Point:62-64 °C
Boiling Point:361.5±22.0 °C(Predicted)
PSA：53.35000
Density:1.20±0.1 g/cm3(Predicted)
LogP:1.66750
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:232.08479225
Heavy Atom Count:17
Complexity:267

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=NN(C(=C1)C(=O)OC)C2=CC=CC=C2

Technology Process of 1H-Pyrazole-5-carboxylic acid, 3-methoxy-1-phenyl-, methyl ester

There total 4 articles about 1H-Pyrazole-5-carboxylic acid, 3-methoxy-1-phenyl-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 77-78-1
dimethyl sulfate

: 3950-18-3
3-hydroxy-1-phenyl-1H-pyrazole-5-carboxylic acid

: 92576-30-2
methyl 3-methoxy-1-phenyl-1H-pyrazole-5-carboxylate

Guidance literature:: With potassium carbonate; In acetone; for 12h; Heating;

Reference yield:

: 1140-69-8
methyl 3-hydroxy-1-phenyl-1H-pyrazole-5-carboxylate

: 74-88-4
methyl iodide

: 92576-30-2
methyl 3-methoxy-1-phenyl-1H-pyrazole-5-carboxylate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 15 ℃; for 12h;

Reference yield:

: 100-63-0
phenylhydrazine

: 762-42-5
dimethyl acetylenedicarboxylate

: 92576-30-2
methyl 3-methoxy-1-phenyl-1H-pyrazole-5-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid / toluene / 5 h / 0 - 115 °C

2: potassium carbonate / N,N-dimethyl-formamide / 12 h / 15 °C

With potassium carbonate; acetic acid; In N,N-dimethyl-formamide; toluene;