3-[(TERT-BUTOXYCARBONYL)AMINO]ETHYL METHANESULFONATE

Base Information

• Chemical Name: 3-[(TERT-BUTOXYCARBONYL)AMINO]ETHYL METHANESULFONATE
• CAS No.: 96628-67-0
• Molecular Formula: C8H17NO5S
• Molecular Weight: 239.293
• Hs Code.: 2924199090
• Mol file: 96628-67-0.mol

Synonyms:N-(tert-butyloxycarbonyl)-2-(methylsulfonyl)ethylamine;methanesulfonic acid 2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]ethyl ester;methanesulfonic acid 2-tert-butoxycarbonylaminoethyl ester;Carbamic acid,[2-[(methylsulfonyl)oxy]ethyl]-,1,1-dimethylethyl ester;t-butyl 2-methanesulfonyloxyethylcarbamate;tert-butyl 2-methylsulfonyloxyethylcarbamate;2-(TERT-BUTOXYCARBONYLAMINO)ETHYL METHANESULFONATE;Boc-aminoethyl mesylate;

Chemical Property of 3-[(TERT-BUTOXYCARBONYL)AMINO]ETHYL METHANESULFONATE

Chemical Property:

• PSA: 93.57000
• LogP: 1.77250

Purity/Quality:

97% ^*data from raw suppliers

3-[(TERT-BUTOXYCARBONYL)AMINO]ETHYL METHANESULFONATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-[(TERT-BUTOXYCARBONYL)AMINO]ETHYL METHANESULFONATE

There total 11 articles about 3-[(TERT-BUTOXYCARBONYL)AMINO]ETHYL METHANESULFONATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-(N-tert-butoxycarbonylamino)ethanol (26690-80-2) + methanesulfonyl chloride (124-63-0) → 2-(tert-butoxycarbonylamino)ethyl methanesulfonate (96628-67-0)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 4h;

Reference yield: 97.0%

2-(N-tert-butoxycarbonylamino)ethanol (26690-80-2) → 2-(tert-butoxycarbonylamino)ethyl methanesulfonate (96628-67-0)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane;

Reference yield: 84.21%

N-BOC-1,2-diaminoethane (57260-73-8) + methanesulfonyl chloride (124-63-0) → 2-(tert-butoxycarbonylamino)ethyl methanesulfonate (96628-67-0)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 2h;

upstream raw materials:

2-(N-tert-butoxycarbonylamino)ethanol

methanesulfonyl chloride

di-tert-butyl dicarbonate

tert-butyl 2-hydroxyethyl carbonate

Downstream raw materials:

tert-butyl 2-azidoethylcarbamate

[2-(2-Hydroxy-ethylamino)-ethyl]-carbamic acid tert-butyl ester

[2-(benzylmethylamino)ethyl]carbamic acid tert-butyl ester

(2-pyrazolo[4,5-b]pyridin-1-ylethyl)carbamic acid tert-butyl ester