[[difluoro(triMethylsilyl)Methyl]thio]-Benzene

Base Information

Chemical Name:[[difluoro(triMethylsilyl)Methyl]thio]-Benzene
CAS No.:536975-49-2
Molecular Formula:C10H14F2SSi
Molecular Weight:232.369
Hs Code.:29309090
Mol file:536975-49-2.mol

Synonyms:(Difluoro(phenylthio)methyl)trimethylsilane;

Suppliers and Price of [[difluoro(triMethylsilyl)Methyl]thio]-Benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Synthonix
[Difluoro(phenylsulfanyl)methyl]trimethylsilane 95+%
1g
$ 480.00

Synthonix
[Difluoro(phenylsulfanyl)methyl]trimethylsilane 95+%
500mg
$ 280.00

Synthonix
[Difluoro(phenylsulfanyl)methyl]trimethylsilane 95+%
250mg
$ 180.00

Synthonix
[Difluoro(phenylsulfanyl)methyl]trimethylsilane 95+%
100mg
$ 100.00

Matrix Scientific
[Difluoro(phenylsulfanyl)methyl]trimethylsilane 95+%
5g
$ 2310.00

Matrix Scientific
[Difluoro(phenylsulfanyl)methyl]trimethylsilane 95+%
1g
$ 885.00

AK Scientific
[Difluoro(phenylthio)methyl]trimethylsilane
5g
$ 3168.00

Total 12 raw suppliers

Chemical Property of [[difluoro(triMethylsilyl)Methyl]thio]-Benzene

Chemical Property:

Boiling Point:208.986 °C at 760 mmHg
Flash Point:80.192 °C
PSA：25.30000
Density:1.074 g/cm³
LogP:4.66880
Solubility.:soluble in most organic solvents, for example hexane, tetrahydrofuran (THF), CH2Cl2, dimethylformamide (DMF), and so on.

Purity/Quality:

99% ^*data from raw suppliers

[Difluoro(phenylsulfanyl)methyl]trimethylsilane 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Physical properties colorless liquid; bp 86–87?C/4 mmHg.
Uses Organofluorine compounds have received remarkable interest in recent years due to their wide-ranging biological effects. The development of general synthetic routes to such compounds and the use of new fluorinated compounds as building blocks are of great importance. Of particular interest is the selective incorporation of the gem-difluoromethylene group ‘CF2’ into organic molecules. The report on the synthesis of PhSCF2SiMe3 was published in 2003 by Prakash et al., and the reagent has become one of the most versatile and efficient nucleophilic (phenylthio)difluoromethylating reagents.When excess potassium t-butoxide was used as a promoter, PhSCF2SiMe3 reacted with diphenyl disulfide to give the corresponding dithioacetal in 85% yield (eq 8).

Technology Process of [[difluoro(triMethylsilyl)Methyl]thio]-Benzene

There total 5 articles about [[difluoro(triMethylsilyl)Methyl]thio]-Benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 81290-20-2
(trifluoromethyl)trimethylsilane

: 108-98-5
thiophenol

: 536975-49-2
phenyl (trimethylsilyl)difluoromethyl sulfide

Guidance literature:: thiophenol; With lithium tetrafluoroborate; lithium hydride; In N,N-dimethyl-formamide; at 25 ℃; for 0.0833333h; Inert atmosphere;

(trifluoromethyl)trimethylsilane; In N,N-dimethyl-formamide; at 25 ℃; Inert atmosphere;
DOI:10.1016/j.jfluchem.2017.07.001