1,2-Bis(4-nitrobenzoyl)hydrazine

Base Information

• Chemical Name: 1,2-Bis(4-nitrobenzoyl)hydrazine
• CAS No.: 4402-22-6
• Molecular Formula: C14H10N4O6
• Molecular Weight: 330.257
• NSC Number: 695050,42950
• DSSTox Substance ID: DTXSID20196015
• Nikkaji Number: J1.053.234E
• Wikidata: Q83069095
• Mol file: 4402-22-6.mol

Synonyms:1,2-Bis(4-nitrobenzoyl)hydrazine;4402-22-6;4-Nitro-N'-(4-nitrobenzoyl)benzohydrazide;NSC42950;NSC 42950;NSC695050;CBDivE_004439;DTXSID20196015;1,2-Di(4-nitrobenzoyl)hydrazine;TVWCBXOCFSQNHO-UHFFFAOYSA-N;NSC-42950;STK017738;AKOS000486164;Hydrazine, 1,2-bis(4-nitrobenzoyl)-;NSC-695050;N'-(4-nitrobenzoyl)-4-nitrobenzohydrazide;FT-0726431;4-Nitro-N'-(4-nitrobenzoyl)benzohydrazide #;4-nitro-N'-[(4-nitrophenyl)carbonyl]benzohydrazide;Benzoic acid, 4-nitro-2-(4-nitrobenzoyl)hydrazide;4-NITRO-BENZOIC ACID N'-(4-NITRO-BENZOYL)-HYDRAZIDE;4-(Hydroxy(oxido)amino)-N'-(4-(hydroxy(oxido)amino)benzoyl)benzohydrazide

Chemical Property of 1,2-Bis(4-nitrobenzoyl)hydrazine

Chemical Property:

• Boiling Point: 670.1°Cat760mmHg
• Flash Point: 359.1°C
• PSA: 149.84000
• Density: 1.489g/cm³
• LogP: 3.40600
• XLogP3: 2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 330.06003405
• Heavy Atom Count: 24
• Complexity: 452

Purity/Quality:

4-nitro-N'-(4-nitrobenzoyl)benzohydrazide(non-preferredname) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1C(=O)NNC(=O)C2=CC=C(C=C2)[N+](=O)[O-])[N+](=O)[O-]

Technology Process of 1,2-Bis(4-nitrobenzoyl)hydrazine

There total 20 articles about 1,2-Bis(4-nitrobenzoyl)hydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-nitrobenzoic acid pentafluorophenyl ester (28078-88-8) + N-amino-(4-nitrophenyl)carboxamide (636-97-5) → N,N'-bis-(4-nitro-benzoyl)-hydrazine (4402-22-6)

Guidance literature:

In N,N-dimethyl-formamide; Ambient temperature;

DOI:10.1016/S0040-4020(97)00149-X

Reference yield: 91.0%

N-amino-(4-nitrophenyl)carboxamide (636-97-5) → N-(3-oxo-2,3-dihydro-1H-pyrazol-4-yl)-benzamide (109702-97-8) + N,N'-bis-(4-nitro-benzoyl)-hydrazine (4402-22-6)

Guidance literature:

With 4-ethoxymethylene-2-phenyl-2-oxazolin-5-one; In 1,4-dioxane; for 0.5h; Heating;

DOI:10.1039/a803973i

Reference yield: 90.0%

4-nitro-benzoyl chloride (122-04-3) → N,N'-bis-(4-nitro-benzoyl)-hydrazine (4402-22-6)

Guidance literature:

With hydrazine hydrate; triethylamine; In tetrahydrofuran; Cooling with ice; Reflux;

DOI:10.1007/s12039-011-0154-8

upstream raw materials:

pyridine

4-nitro-benzoyl chloride

thiosemicarbazide

3-(4-nitro-benzoylhydrazono)-butyric acid ethyl ester

Downstream raw materials:

p-amino-N'-(p-aminobenzoyl)benzohydrazide

bis-(4-nitro-phenyl)-[1,3,4]oxadiazole

2, 5-bis(4-nitrophenyl)-1,3,4-thiadiazole

2-(4-nitrophenyl)-5-phenyl-1,3,4-oxadiazole