2-(5-phenyl-2H-tetrazol-2-yl)acetohydrazide

Base Information

• Chemical Name: 2-(5-phenyl-2H-tetrazol-2-yl)acetohydrazide
• CAS No.: 67037-01-8
• Molecular Formula: C9H10N6O
• Molecular Weight: 218.218
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID30351517
• Wikidata: Q82127986
• Mol file: 67037-01-8.mol

Synonyms:2-(5-phenyl-2H-tetrazol-2-yl)acetohydrazide;67037-01-8;2-(5-phenyltetrazol-2-yl)acetohydrazide;2-(5-phenyl-2H-1,2,3,4-tetrazol-2-yl)acetohydrazide;2-(5-phenyl-2H-tetraazol-2-yl)acetohydrazide;(5-Phenyl-tetrazol-2-yl)-acetic acid hydrazide;Oprea1_683874;Oprea1_838017;SCHEMBL8215669;2-(5-phenyl-2h-1,2,3,4-tetraazol-2-yl)acetohydrazide;DTXSID30351517;MFCD00215520;STK346868;AKOS000309371;5-phenyltetrazol-2-ylacetic acid hydrazide;EN300-08958;6F-903;A914396;(5-PHENYL-TETRAZOL-2-YL)-ACETICACIDHYDRAZIDE;Z55992881

Chemical Property of 2-(5-phenyl-2H-tetrazol-2-yl)acetohydrazide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 98.72000
• Density: 1.51g/cm³
• LogP: 0.42120
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 218.09160896
• Heavy Atom Count: 16
• Complexity: 242

Purity/Quality:

97% ^*data from raw suppliers

2-(5-phenyl-2H-tetraazol-2-yl)acetohydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=NN(N=N2)CC(=O)NN

Technology Process of 2-(5-phenyl-2H-tetrazol-2-yl)acetohydrazide

There total 6 articles about 2-(5-phenyl-2H-tetrazol-2-yl)acetohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(5-phenyltetrazol-2-yl)acetic acid methyl ester (25828-29-9) → 2-(5-phenyl-2H-tetrazole-2-yl)acetohydrazide (67037-01-8)

Guidance literature:

With hydrazine hydrate; In methanol; Heating;

DOI:10.3906/kim-1307-13

Reference yield: 95.0%

5-phenyl-2-tetrazolylacetic acid ethyl ester (21054-65-9) → 2-(5-phenyl-2H-tetrazole-2-yl)acetohydrazide (67037-01-8)

Guidance literature:

With hydrazine hydrate; In ethanol; for 8h; Heating;

DOI:10.1002/jhet.5570170709

Reference yield:

5-phenyl-2H-1,2,3,4-tetrazole (18039-42-4) → 2-(5-phenyl-2H-tetrazole-2-yl)acetohydrazide (67037-01-8)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol, sodium / 16 h / Heating

2: 99percent N₂H₄*H₂O / ethanol / 8 h / Heating

With ethanol; sodium; hydrazine hydrate; In ethanol;

upstream raw materials:

5-phenyl-2-tetrazolylacetic acid ethyl ester

2-(5-phenyl-2H-tetrazol-2-yl)acetic acid chloride

5-phenyl-2H-tetrazolylacetic acid

benzonitrile

Downstream raw materials:

1-(5-phenyl-2H-tetrazol-2-ylacetyl)-4-(2-ethoxyphenyl)thiosemicarbazide