2-(4-Methoxyphenyl)oxazolidine

Base Information

• Chemical Name: 2-(4-Methoxyphenyl)oxazolidine
• CAS No.: 66670-98-2
• Molecular Formula: C10H13 N O2
• Molecular Weight: 179.2157
• NSC Number: 69075
• Nikkaji Number: J529.611K
• Mol file: 66670-98-2.mol

Synonyms:NSC69075;NCIOpen2_000489;2-(p-methoxyphenyl) oxazolidine;SCHEMBL14197966;NSC-69075;66670-98-2

Chemical Property of 2-(4-Methoxyphenyl)oxazolidine

Chemical Property:

• Vapor Pressure: 0.0012mmHg at 25°C
• Boiling Point: 299.3°Cat760mmHg
• Flash Point: 116.2°C
• Density: 1.092g/cm³
• XLogP3: 1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 179.094628657
• Heavy Atom Count: 13
• Complexity: 155

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C2NCCO2

Technology Process of 2-(4-Methoxyphenyl)oxazolidine

There total 2 articles about 2-(4-Methoxyphenyl)oxazolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methoxy-benzaldehyde (123-11-5) + ethanolamine (141-43-5) → 2-(4-methoxy-phenyl)-oxazolidine (66670-98-2)

Guidance literature:

In acetonitrile; at 20 ℃; for 4h;

DOI:10.1055/s-2007-982571

Reference yield:

→ 2-(4-methoxy-phenyl)-oxazolidine (66670-98-2)

Guidance literature:

Aminoethanol,/BRN= 471382/;

Reference yield:

2-(4-methoxy-phenyl)-oxazolidine (66670-98-2) + propoxycarbonyl chloride (109-61-5) → propyl 2-(4-methoxyphenyl)oxazolidine-3-carboxylate

Guidance literature:

With dmap; In toluene; at 20 ℃; for 1h;

DOI:10.1016/j.bmcl.2018.12.061

upstream raw materials:

4-methoxy-benzaldehyde

ethanolamine

Downstream raw materials:

2,2'-bis-(4-methoxy-phenyl)-3,3'-malonyl-bis-oxazolidine

2-(4-methoxyphenyl)-4,5-dihydrooxazole