L-Mannitol

Base Information

• Chemical Name: L-Mannitol
• CAS No.: 643-01-6
• Molecular Formula: C6H14O6
• Molecular Weight: 182.174
• Hs Code.: 29400090
• DSSTox Substance ID: DTXSID40214523
• Nikkaji Number: J13.213F
• Wikidata: Q27117350
• Metabolomics Workbench ID: 55752
• Mol file: 643-01-6.mol

Synonyms:L-Mannitol;643-01-6;(2S,3S,4S,5S)-Hexane-1,2,3,4,5,6-hexaol;(2S,3S,4S,5S)-hexane-1,2,3,4,5,6-hexol;L-mitobronitol;C6-H14-O6;SCHEMBL25330;D-Mannitol, EP, USP grade;CHEBI:38030;DTXSID40214523;MFCD00154039;AKOS016845898;AC-13700;HY-139312;CS-0197886;M1084;D91442;A867906;WURCS=2.0/1,1,0/[h2211h]/1/;J-200008;W-203389;Q27117350;F0430C81-EA3D-4324-863D-08AB2852F39D

Chemical Property of L-Mannitol

Chemical Property:

• Appearance/Colour: white crystalline powder
• Vapor Pressure: 7.22E-12mmHg at 25°C
• Melting Point: 165 °C
• Refractive Index: -30 ° (C=5, H2O)
• Boiling Point: 494.9 °C at 760 mmHg
• PKA: 13.14±0.20(Predicted)
• Flash Point: 292.5 °C
• PSA: 121.38000
• Density: 1.596 g/cm³
• LogP: -3.58540
• Storage Temp.: Inert atmosphere,Room Temperature
• XLogP3: -3.1
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 5
• Exact Mass: 182.07903816
• Heavy Atom Count: 12
• Complexity: 105

Purity/Quality:

98%, ^*data from raw suppliers

L-Mannitol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C(C(C(CO)O)O)O)O)O
• Isomeric SMILES: C([C@@H]([C@@H]([C@H]([C@H](CO)O)O)O)O)O

Technology Process of L-Mannitol

There total 72 articles about L-Mannitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.2%

cellulose (9004-34-6) → propylene glycol (57-55-6,63625-56-9) + ethylene glycol (107-21-1) + isopropyl alcohol (67-63-0,8013-70-5) + sorbitol (50-70-4,69-65-8,87-78-5,133-43-7,488-44-8,488-45-9,608-66-2,643-01-6,643-03-8,5552-13-6,6706-59-8,24557-79-7,25878-23-3,26566-34-7,45007-61-2,60660-56-2,60660-57-3,60660-58-4,132747-27-4)

Guidance literature:

With water; at 220 ℃; for 0.5h; under 52505.3 Torr; Temperature; Pressure;

Reference yield: 33.6%

cellulose (9004-34-6) → propylene glycol (57-55-6,63625-56-9) + isopropyl alcohol (67-63-0,8013-70-5) + sorbitol (50-70-4,69-65-8,87-78-5,133-43-7,488-44-8,488-45-9,608-66-2,643-01-6,643-03-8,5552-13-6,6706-59-8,24557-79-7,25878-23-3,26566-34-7,45007-61-2,60660-56-2,60660-57-3,60660-58-4,132747-27-4)

Guidance literature:

With water; at 220 ℃; for 0.5h; under 45004.5 Torr; Temperature; Pressure;

Reference yield: 15.8%

cellulose (9004-34-6) → propylene glycol (57-55-6,63625-56-9) + sorbitol (50-70-4,69-65-8,87-78-5,133-43-7,488-44-8,488-45-9,608-66-2,643-01-6,643-03-8,5552-13-6,6706-59-8,24557-79-7,25878-23-3,26566-34-7,45007-61-2,60660-56-2,60660-57-3,60660-58-4,132747-27-4)

Guidance literature:

With hydrogen; In water; at 239.84 ℃; for 4h; under 30003 Torr;

DOI:10.1039/c2gc35685f

upstream raw materials:

L-mannose

L-mannono-1,4-lactone

L-mannonic γ-lactone

L-mannono-1,4-lactone

Downstream raw materials:

1,6-dichloro-2S,3S,4S,5S-hexanetetraol

mannitol hexabenzoate

L-mannitol hexaacetate

1,6-Di-O-methansulfonyl-L-mannit