Dichloromannitol

Base Information

• Chemical Name: Dichloromannitol
• CAS No.: 7251-85-6
• Molecular Formula: C6H12Cl2O4
• Molecular Weight: 219.065
• NSC Number: 117358,232023,231339,20665
• DSSTox Substance ID: DTXSID90943098
• Mol file: 7251-85-6.mol

Synonyms:Dichloromannitol;NSC 20665;1,6-Dichloro-1,6-dideoxymannitol;1,6-Dichloro-1,6-didesoxy-D-mannitol;Dichlorodulcitol;MANNITOL, 1,6-DICHLORO-1,6-DIDEOXY-, (D)-;20847-01-2;D-Mannitol, 1,6-dichloro-1,6-dideoxy-;UNII-XXN9QHY331;NSC-20665;7251-85-6;C6H12Cl2O4;C6-H12-Cl2-O4;DTXSID90943098;1,6-Dichloro-1,6-dideoxyhexitol;NSC20665;Galactitol,6-dichloro-1,6-dideoxy-;NSC117358;NSC231339;NSC232023;D-Mannitol,6-dichloro-1,6-dideoxy-;D-Galactitol,6-dichloro-1,6-dideoxy-;NSC-117358;NSC-231339;NSC-232023;Mannitol,6-dichloro-1,6-dideoxy-, D-;LS-89270;D-Galactitol, 1,6-dichloro-1,6-dideoxy-;Mannitol, 1,6-dichloro-1,6-dideoxy-, D-;58073-31-7

Chemical Property of Dichloromannitol

Chemical Property:

• Boiling Point: 480.6°Cat760mmHg
• Flash Point: 244.5°C
• Density: 1.544g/cm³
• XLogP3: -0.6
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 218.0112642
• Heavy Atom Count: 12
• Complexity: 110

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C(C(C(C(C(CCl)O)O)O)O)Cl

Technology Process of Dichloromannitol

There total 7 articles about Dichloromannitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

mannitol (69-65-8) → 1,6-dichloro-2S,3S,4S,5S-hexanetetraol (7251-85-6,58073-31-7)

Guidance literature:

With methanesulfonyl chloride; In N,N-dimethyl-formamide;

DOI:10.1016/S0040-4039(00)79831-5

Reference yield:

mannitol (69-65-8) → 1,6-dichloro-2S,3S,4S,5S-hexanetetraol (7251-85-6,58073-31-7) + 1,5:3,6-dianhydro-D-mannitol (148706-62-1) + 1,4-anhydro-D-mannitol (7726-97-8) + 1,5-anhydro-D-mannitol (492-93-3,53319-04-3)

Guidance literature:

at 100 ℃; weitereProd_.:Dianhydrohexit;1-Chlor-3.6-anhydro-1-desoxy-D-mannit;2-Chlor-1.4;3.6-dianhydro-2-desoxy-D-mannit;Dichloranhydro-didesoxy-mannit;

DOI:10.1039/jr9470000433

Reference yield:

→ 1,6-dichloro-2S,3S,4S,5S-hexanetetraol (7251-85-6,58073-31-7)

Guidance literature:

With hydrogenchloride; acetone; at 25 ℃;

DOI:10.1039/jr9460000384

upstream raw materials:

mannitol

L-mannitol

hydrogenchloride

acetone

Downstream raw materials:

1,4:3,6-dianhydro-D-mannitol

2,5;3,6-dianhydro-D-glucitol

isomannide dinitrate

bis-O-(toluene-4-sulfonyl)-2,5;3,6-dianhydro-D-glucitol