Benzyl diphenylphosphinate

Base Information

• Chemical Name: Benzyl diphenylphosphinate
• CAS No.: 5573-42-2
• Molecular Formula: C19H17O2P
• Molecular Weight: 308.317
• NSC Number: 171144
• UNII: JUK5J57CCL
• DSSTox Substance ID: DTXSID90204277
• Nikkaji Number: J104.212B
• Wikidata: Q83077712
• Mol file: 5573-42-2.mol

Synonyms:Benzyl diphenylphosphinate;5573-42-2;diphenylphosphoryloxymethylbenzene;JUK5J57CCL;Phosphinic acid, diphenyl-, phenylmethyl ester;UNII-JUK5J57CCL;NSC 171144;Phosphinic acid, diphenyl-, benzyl ester;NSC171144;NSC-171144;Benzyl diphenylphosphinate #;Phosphinic acid, benzyl ester;SCHEMBL389123;DTXSID90204277;BUBAPAVHHCZZMA-UHFFFAOYSA-N;Phosphinic acid, phenylmethyl ester;Phenylmethyl P,P-diphenylphosphinate;Diphenyl-phosphinic acid benzyl ester;Phosphinic acid, P,P-diphenyl-, phenylmethyl ester

Chemical Property of Benzyl diphenylphosphinate

Chemical Property:

• Vapor Pressure: 1.01E-07mmHg at 25°C
• Boiling Point: 445.7°Cat760mmHg
• Flash Point: 236.7°C
• PSA: 36.11000
• Density: 1.19g/cm³
• LogP: 4.13230
• XLogP3: 4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 308.09661678
• Heavy Atom Count: 22
• Complexity: 342

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)COP(=O)(C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of Benzyl diphenylphosphinate

There total 26 articles about Benzyl diphenylphosphinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

diphenyl-phosphinic acid (1707-03-5) + benzyl chloride (100-44-7) → (benzyloxy)di(phenyl)phosphine oxide (5573-42-2)

Guidance literature:

With triethylamine; In neat (no solvent); at 120 ℃; for 12h; Schlenk technique;

DOI:10.1016/j.tetlet.2021.153529

Reference yield: 98.0%

diphenyl-phosphinic acid (1707-03-5) + toluene (108-88-3,15644-74-3,16713-13-6) → (benzyloxy)di(phenyl)phosphine oxide (5573-42-2)

Guidance literature:

With tert.-butylhydroperoxide; tetra-(n-butyl)ammonium iodide; In dichloromethane; at 80 ℃; for 12h; Schlenk technique;

Reference yield: 97.0%

diphenyl-phosphinic acid (1707-03-5) + benzyl bromide (100-39-0) → (benzyloxy)di(phenyl)phosphine oxide (5573-42-2)

Guidance literature:

With caesium carbonate; In acetonitrile; at 100 ℃; for 12h; Reagent/catalyst; Solvent; Inert atmosphere;

DOI:10.1016/j.tet.2014.10.013

upstream raw materials:

cinnamic nitrile

Benzyl N-benzylidene-α-(diphenylphosphinoyl)glycinate

maleonitrile

crotonic acid methyl ester

Downstream raw materials:

N-benzyl-P,P-diphenylphosphinic amide

benzyl cyclohexyl ether

(2-(benzyloxy)ethyl)benzene

dibenzyl ether