1-(2-Hydroxyphenyl)-2-methylpropan-1-one

Base Information

Chemical Name:1-(2-Hydroxyphenyl)-2-methylpropan-1-one
CAS No.:6640-69-3
Molecular Formula:C10H12O2
Molecular Weight:164.204
Hs Code.:
NSC Number:49021
DSSTox Substance ID:DTXSID40985049
Nikkaji Number:J593.322F
Wikidata:Q82972468

Synonyms:1-(2-hydroxyphenyl)-2-methylpropan-1-one;6640-69-3;NSC49021;2'-Hydroxyisobutyrophenone;SCHEMBL5415081;DTXSID40985049;NSC-49021;1-(2-hydroxyphenyl)-2-methyl-1-propanone

Suppliers and Price of 1-(2-Hydroxyphenyl)-2-methylpropan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 1-(2-Hydroxyphenyl)-2-methylpropan-1-one

Chemical Property:

Vapor Pressure:0.0171mmHg at 25°C
Boiling Point:246.6°Cat760mmHg
Flash Point:101.3°C
Density:1.074g/cm³
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:164.083729621
Heavy Atom Count:12
Complexity:163

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C(=O)C1=CC=CC=C1O

Technology Process of 1-(2-Hydroxyphenyl)-2-methylpropan-1-one

There total 18 articles about 1-(2-Hydroxyphenyl)-2-methylpropan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 64686-76-6
1-[2-(benzyloxy)phenyl]-2-methylpropan-1-one

: 6640-69-3
1-(2-hydroxyphenyl)-2-methylpropan-1-one

Guidance literature:: With palladium on activated charcoal; hydrogen; In methanol; at 20 ℃; for 2h;

Reference yield: 91.0%

: 611-20-1
salicylonitrile

: 1068-55-9
isopropylmagnesium chloride

: 6640-69-3
1-(2-hydroxyphenyl)-2-methylpropan-1-one

Guidance literature:: salicylonitrile; isopropylmagnesium chloride; In tetrahydrofuran; for 2h; Reflux;

With sulfuric acid; water; In tetrahydrofuran; at 80 ℃; for 1h; Cooling with ice;
DOI:10.1371/journal.pone.0112059

Reference yield: 84.0%

: 20279-29-2
phenyl isobutyrate

: 34917-91-4
4-hydroxyisobutyrophenone

: 6640-69-3
1-(2-hydroxyphenyl)-2-methylpropan-1-one

Guidance literature:: With methanesulfonic acid; Methanesulfonic anhydride; at 65 ℃; regioselective reaction; Inert atmosphere;
DOI:10.1055/s-0032-1316568