fructosylvaline

Base Information

• Chemical Name: fructosylvaline
• CAS No.: 10003-64-2
• Molecular Formula: C₁₁H₂₁NO₇
• Molecular Weight: 279.29
• Hs Code.: 29225090
• Mol file: 10003-64-2.mol

Synonyms:Fructose,1-[(L-1-carboxy-2-methylpropyl)amino]-1-deoxy-, D- (6CI,7CI,8CI);1-Deoxy-1-L-valino-D-fructose; 1-L-Valine-1-deoxy-D-fructose;1-Valino-1-deoxy-D-fructose; Fructose-valine; Fructosyl-valine; N-Fructosylvaline

Chemical Property of fructosylvaline

Chemical Property:

• Melting Point: 112-114°C
• PSA: 139.48000
• LogP: -2.12240
• Storage Temp.: Refrigerator, Under Inert Atmosphere
• Solubility.: Methanol (Slightly), Water (Slightly)

Purity/Quality:

98%,99%, ^*data from raw suppliers

Fructose Valine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: An Amadori compound having the potential to alter cellular adhesion, inhibit cancer metastasis and induce apoptosis.

Technology Process of fructosylvaline

There total 2 articles about fructosylvaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-valine (72-18-4,25609-85-2,7004-03-7,921-10-8) + D-glucose (50-99-7) → N-(1-deoxy-D-fructos-1-yl)-L-valine (10003-64-2)

Guidance literature:

With methanol;

Reference yield:

methanol (67-56-1) + D-Fructose (57-48-7,18875-34-8) + L-valine (72-18-4,25609-85-2,7004-03-7,921-10-8) + oxalic acid (144-62-7,97993-78-7) → N-D-glucose-2-yl-L-valine (77464-67-6) + N-(1-deoxy-D-fructos-1-yl)-L-valine (10003-64-2)

Guidance literature:

analoge Reaktionen mit L-Phenylalanin und mit L-Asparaginsaeure;

Reference yield: 84.0%

N-(1-deoxy-D-fructos-1-yl)-L-valine (10003-64-2) → N-(1-Desoxy-D-fructos-1-yl)-N-nitroso-L-valin (99789-40-9)

Guidance literature:

With hydrogenchloride; sodium nitrite; In water;

DOI:10.1016/0008-6215(87)80131-3

upstream raw materials:

L-valine

D-glucose

methanol

D-Fructose

Downstream raw materials:

N-(1-Desoxy-D-fructos-1-yl)-N-nitroso-L-valin

Refernces