3-methoxy-N,N-dimethylpropionamide

Base Information

• Chemical Name: 3-methoxy-N,N-dimethylpropionamide
• CAS No.: 53185-52-7
• Molecular Formula: C6H13 N O2
• Molecular Weight: 131.175
• Hs Code.: 2924199090
• European Community (EC) Number: 258-420-7
• DSSTox Substance ID: DTXSID8068836
• Nikkaji Number: J295.906B
• Wikidata: Q81995602
• Mol file: 53185-52-7.mol

Synonyms:N,N-Dimethyl-3-methoxypropionamide

Chemical Property of 3-methoxy-N,N-dimethylpropionamide

Chemical Property:

• Vapor Pressure: 0.591mmHg at 25°C
• Boiling Point: 188.7°Cat760mmHg
• PKA: -0.56±0.70(Predicted)
• Flash Point: 67.9°C
• PSA: 29.54000
• Density: 0.948g/cm³
• LogP: 0.11110
• Water Solubility.: 500g/L at 21.5℃
• XLogP3: -0.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 131.094628657
• Heavy Atom Count: 9
• Complexity: 91.1

Purity/Quality:

98%, ^*data from raw suppliers

3-Methoxy-N,N-dimethylpropanamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)C(=O)CCOC

Technology Process of 3-methoxy-N,N-dimethylpropionamide

There total 6 articles about 3-methoxy-N,N-dimethylpropionamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

methyl 3-methoxypropionate (3852-09-3) + dimethyl amine (124-40-3) → β-methoxy-N,N-dimethylpropionic acid amide (53185-52-7)

Guidance literature:

With zinc(II) trifluoroacetate; at 0 - 40 ℃; for 8h; Reagent/catalyst; Autoclave;

Reference yield:

3-Methoxypropionic acid (2544-06-1) + dimethyl amine (124-40-3) → β-methoxy-N,N-dimethylpropionic acid amide (53185-52-7)

Guidance literature:

at 100 ℃; under 11251.1 Torr; Temperature; Pressure;

Reference yield:

C6H12O4 + C10H18O6 + dimethyl amine (124-40-3) → β-methoxy-N,N-dimethylpropionic acid amide (53185-52-7)

Guidance literature:

at 60 ℃; for 6h; Autoclave;

upstream raw materials:

methyl 3-methoxypropionate

dimethyl amine

methanol

N,N-Dimethylacrylamide

Downstream raw materials:

N,N-Dimethylacrylamide