1-bromo-4-propan-2-yloxy-benzene

Base Information

• Chemical Name: 1-bromo-4-propan-2-yloxy-benzene
• CAS No.: 6967-88-0
• Molecular Formula: C9H11BrO
• Molecular Weight: 215.09
• Hs Code.: 2909309090
• Mol file: 6967-88-0.mol

Synonyms:1-bromo-4-propan-2-yloxy-benzene

Chemical Property of 1-bromo-4-propan-2-yloxy-benzene

Chemical Property:

• Vapor Pressure: 0.0628mmHg at 25°C
• Boiling Point: 239.2°C at 760 mmHg
• Flash Point: 106.6°C
• PSA: 9.23000
• Density: 1.319g/cm³
• LogP: 3.23630

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-Bromo-4-isopropoxybenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-bromo-4-propan-2-yloxy-benzene

There total 9 articles about 1-bromo-4-propan-2-yloxy-benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

isopropoxybenzene (2741-16-4) → 1-bromo-4-isopropoxybenzene (6967-88-0)

Guidance literature:

With aluminum oxide; sodium chlorite; water; manganese(III) acetylacetonate; sodium bromide; In dichloromethane; at 20 ℃; for 1.83333h;

DOI:10.1080/00304949809355283

Reference yield: 97.0%

4-bromo-phenol (106-41-2) + isopropyl bromide (75-26-3) → 1-bromo-4-isopropoxybenzene (6967-88-0)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; acetone; at 80 ℃; for 48h;

DOI:10.1021/jm2015809

Reference yield: 97.0%

4-bromo-phenol (106-41-2) + isopropyl alcohol (67-63-0,8013-70-5) → 1-bromo-4-isopropoxybenzene (6967-88-0)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃; for 12h; Inert atmosphere;

DOI:10.1021/jacs.0c01714

upstream raw materials:

2-iodo-propane

4-bromo-phenol

propene

isopropoxybenzene

Downstream raw materials:

(2-isopropoxy-3-methoxy-phenyl)-(4-isopropoxy-phenyl)-methanol

4-(isopropoxy)phenylboronic acid

1-isopropoxy-4-isopropylbenzene

1-(4-isopropoxy-phenyl)-2,2,4,4-tetramethyl-3-(4-pyridin-2-yl-piperazin-1-yl)-cyclobutanol

Refernces

• 1、 Fan, Jiali,Wei, Qiancheng,Zhu, Ershu,Gao, Jing,Cheng, Xiamin,Lu, Yongna,Loh, Teck-Peng. "Visible light-induced mono-bromination of arenes with BrCCl3". supporting information. p. 5977 - 5980. Retrieved 2021/06/18.
• 2、 Mills, L. Reginald,Graham, Joshua M.,Patel, Purvish,Rousseaux, Sophie A. L.. "Ni-Catalyzed Reductive Cyanation of Aryl Halides and Phenol Derivatives via Transnitrilation". supporting information. p. 19257 - 19262. Retrieved 2019/12/02.