Benzene, 1,1'-(1,2-cyclopropanediyl)bis[4-methoxy-

Base Information

• Chemical Name: Benzene, 1,1'-(1,2-cyclopropanediyl)bis[4-methoxy-
• CAS No.: 3718-51-2
• Molecular Formula: C17H18 O2
• Molecular Weight: 254.329
• NSC Number: 86500
• DSSTox Substance ID: DTXSID50292933
• Nikkaji Number: J461.831I
• Mol file: 3718-51-2.mol

Synonyms:3718-51-2;STK010016;1,1'-cyclopropane-1,2-diylbis(4-methoxybenzene);NSC86500;1,2-Bis(4-methoxyphenyl)cyclopropane;benzene, 1,1'-(1,2-cyclopropanediyl)bis[4-methoxy-;SCHEMBL11064726;DTXSID50292933;YTFKRSWDEPYBKW-UHFFFAOYSA-N;NSC-86500;AKOS003597420

Chemical Property of Benzene, 1,1'-(1,2-cyclopropanediyl)bis[4-methoxy-

Chemical Property:

• Boiling Point: 369.5°Cat760mmHg
• Flash Point: 143.5°C
• Density: 1.107g/cm³
• XLogP3: 4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 254.130679813
• Heavy Atom Count: 19
• Complexity: 247

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C2CC2C3=CC=C(C=C3)OC

Technology Process of Benzene, 1,1'-(1,2-cyclopropanediyl)bis[4-methoxy-

There total 3 articles about Benzene, 1,1'-(1,2-cyclopropanediyl)bis[4-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methoxy-benzaldehyde (123-11-5) → 1,2-bis(4-methoxyphenyl)cyclopropane (3718-51-2)

Guidance literature:

Multi-step reaction with 2 steps

1: NaOH / H₂O / Ambient temperature

2: 1.) hydrazine, 2.) KOH / 1.) diethylene glycol, 190 deg C, 1.5 h, 2.) 200 deg C, 3 h

With potassium hydroxide; sodium hydroxide; hydrazine; In water;

DOI:10.1080/00268948008071428

Reference yield:

1-(4-methoxyphenyl)ethanone (100-06-1) → 1,2-bis(4-methoxyphenyl)cyclopropane (3718-51-2)

Guidance literature:

Multi-step reaction with 2 steps

1: NaOH / H₂O / Ambient temperature

2: 1.) hydrazine, 2.) KOH / 1.) diethylene glycol, 190 deg C, 1.5 h, 2.) 200 deg C, 3 h

With potassium hydroxide; sodium hydroxide; hydrazine; In water;

DOI:10.1080/00268948008071428

Reference yield:

4,4'-dimethoxychalcone (2373-89-9) → 1,2-bis(4-methoxyphenyl)cyclopropane (3718-51-2)

Guidance literature:

With potassium hydroxide; hydrazine; Yield given. Multistep reaction; 1.) diethylene glycol, 190 deg C, 1.5 h, 2.) 200 deg C, 3 h;

DOI:10.1080/00268948008071428

upstream raw materials:

4,4'-dimethoxychalcone

4-methoxy-benzaldehyde

1-(4-methoxyphenyl)ethanone

Downstream raw materials:

3,5-Bis(p-methoxyphenyl)-4,5-dihydroisoxazole

C₂₀H₂₆O₃

1,3-bis(4-methoxyphenyl)propane

1,3-bis(4-methoxyphenyl)-1-hydroxypropane-3-one