2,6-Dimethoxy-N,N,N-trimethylpyrimidin-4-aminium chloride

Base Information

• Chemical Name: 2,6-Dimethoxy-N,N,N-trimethylpyrimidin-4-aminium chloride
• CAS No.: 77767-96-5
• Molecular Formula: C9H16N3O2+
• Molecular Weight: 233.698
• DSSTox Substance ID: DTXSID80506818
• NSC Number: 51096
• Mol file: 77767-96-5.mol

Synonyms:77767-96-5;2,6-Dimethoxy-N,N,N-trimethylpyrimidin-4-aminium chloride;DTXSID80506818;NSC51096;NSC-51096

Chemical Property of 2,6-Dimethoxy-N,N,N-trimethylpyrimidin-4-aminium chloride

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: g/cm³
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 233.0931045
• Heavy Atom Count: 15
• Complexity: 181

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[N+](C)(C)C1=CC(=NC(=N1)OC)OC.[Cl-]

Technology Process of 2,6-Dimethoxy-N,N,N-trimethylpyrimidin-4-aminium chloride

There total 1 articles about 2,6-Dimethoxy-N,N,N-trimethylpyrimidin-4-aminium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

6-chloro-2,4-dimethoxypyrimidine (6320-15-6) + trimethylamine (75-50-3) → Trimethyl-4-(2,6-dimethoxypyrimidinyl)ammoniumchlorid (77767-96-5)

Guidance literature:

In benzene; 1) 0 deg C; 2) room temperature, 12h;

Reference yield: 85.0%

tetraethylammoniumcyanide (13435-20-6) + Trimethyl-4-(2,6-dimethoxypyrimidinyl)ammoniumchlorid (77767-96-5) → 4-Cyan-2,6-dimethoxypyrimidin (100868-70-0)

Guidance literature:

In dichloromethane; for 0.5h; Ambient temperature;

Reference yield:

Trimethyl-4-(2,6-dimethoxypyrimidinyl)ammoniumchlorid (77767-96-5) → sulfadimethoxine (122-11-2)

Guidance literature:

With acetamide;

DOI:10.1007/BF00903598

upstream raw materials:

6-chloro-2,4-dimethoxypyrimidine

trimethylamine

Downstream raw materials:

4-Cyan-2,6-dimethoxypyrimidin

sulfadimethoxine