5-bromo-ethylenediamine-N,N'-bis(2-hydroxyphenylacetic acid)

Base Information

• Chemical Name: 5-bromo-ethylenediamine-N,N'-bis(2-hydroxyphenylacetic acid)
• CAS No.: 74304-83-9
• Molecular Formula: C18H18 Br2 N2 O6
• Molecular Weight: 0
• Mol file: 74304-83-9.mol

Synonyms:5-bromo-ethylenediamine-N,N’-bis(2-hydroxyphenylacetic acid)

Chemical Property of 5-bromo-ethylenediamine-N,N'-bis(2-hydroxyphenylacetic acid)

Chemical Property:

• Boiling Point: 690.1oC at 760 mmHg
• Flash Point: 371.2oC
• PSA: 139.12000
• Density: 1.807g/cm3
• LogP: 3.53540

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-bromo-ethylenediamine-N,N'-bis(2-hydroxyphenylacetic acid)

There total 2 articles about 5-bromo-ethylenediamine-N,N'-bis(2-hydroxyphenylacetic acid) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

4-bromo-phenol (106-41-2) + sodium dichloroacetate (2156-56-1) + ethylenediamine (107-15-3,85404-18-8) → ethylenediamine-N,N'-bis(α-2-hydroxy-5-bromophenyl)acetic acid (74304-83-9)

Guidance literature:

With sodium hydroxide; In methanol; water; at 85 ℃; for 24h;

DOI:10.1002/jps.2600690528

Reference yield:

dichloro-acetic acid (79-43-6) + 4-bromo-phenol (106-41-2) + ethylenediamine (107-15-3,85404-18-8) → ethylenediamine-N,N'-bis(α-2-hydroxy-5-bromophenyl)acetic acid (74304-83-9)

Guidance literature:

With sodium hydroxide; In methanol; water; at 90 ℃; for 5h;

Reference yield:

methanol (67-56-1) + ethylenediamine-N,N'-bis(α-2-hydroxy-5-bromophenyl)acetic acid (74304-83-9) → (5-Bromo-2-hydroxy-phenyl)-(2-{[(5-bromo-2-hydroxy-phenyl)-methoxycarbonyl-methyl]-amino}-ethylamino)-acetic acid methyl ester; hydrochloride (115061-99-9,115062-14-1)

Guidance literature:

With hydrogenchloride; for 6h; Heating;

upstream raw materials:

dichloro-acetic acid

4-bromo-phenol

ethylenediamine

sodium dichloroacetate

Downstream raw materials:

(5-Bromo-2-hydroxy-phenyl)-(2-{[(5-bromo-2-hydroxy-phenyl)-methoxycarbonyl-methyl]-amino}-ethylamino)-acetic acid methyl ester; hydrochloride