1-((4-methylphenyl)methyl)-1H-pyrrole-2,5-dione

Base Information

Chemical Name:1-((4-methylphenyl)methyl)-1H-pyrrole-2,5-dione
CAS No.:42867-34-5
Molecular Formula:C12H11NO2
Molecular Weight:201.225
Hs Code.:
NSC Number:186043
DSSTox Substance ID:DTXSID00307026
Nikkaji Number:J466.404C
Wikidata:Q82054350
Mol file:42867-34-5.mol

Synonyms:42867-34-5;1-(4-methylbenzyl)-1H-pyrrole-2,5-dione;1-((4-methylphenyl)methyl)-1H-pyrrole-2,5-dione;1-[(4-methylphenyl)methyl]pyrrole-2,5-dione;1-[(4-Methylphenyl)methyl]-1H-pyrrole-2,5-dione;N-((4-Methylphenyl)methyl)maleimide;NSC186043;Cyto9H11;Maybridge3_005976;1H-Pyrrole-2,5-dione,1-[(4-methylphenyl)methyl]-;SCHEMBL4800190;DTXSID00307026;HMS1447P14;STL020772;AKOS000249135;NSC-186043;IDI1_017363;FT-0605458;VU0513153-1;F3205-0019

Suppliers and Price of 1-((4-methylphenyl)methyl)-1H-pyrrole-2,5-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-((4-METHYLPHENYL)METHYL)MALEIMIDE 95.00%
1G
$ 979.60

Total 9 raw suppliers

Chemical Property of 1-((4-methylphenyl)methyl)-1H-pyrrole-2,5-dione

Chemical Property:

Vapor Pressure:3.63E-05mmHg at 25°C
Refractive Index:1.612
Boiling Point:353.3 °C at 760 mmHg
PKA:-2.32±0.20(Predicted)
Flash Point:162 °C
PSA：37.38000
Density:1.252 g/cm³
LogP:1.35790
XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:201.078978594
Heavy Atom Count:15
Complexity:283

Purity/Quality:

99% ^*data from raw suppliers

N-((4-METHYLPHENYL)METHYL)MALEIMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)CN2C(=O)C=CC2=O

Technology Process of 1-((4-methylphenyl)methyl)-1H-pyrrole-2,5-dione

There total 6 articles about 1-((4-methylphenyl)methyl)-1H-pyrrole-2,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 108-31-6
maleic anhydride

: 104-84-7
para-methylbenzylamine

: 42867-34-5
1-((4-methylphenyl)methyl)-1H-pyrrole-2,5-dione

Guidance literature:: maleic anhydride; para-methylbenzylamine; In diethyl ether; at 20 ℃; for 1h;

With sodium acetate; acetic anhydride; at 70 ℃; for 6h;
DOI:10.1039/c2ob26699g

Reference yield: 41.0%

: 64-17-5
ethanol

: 94054-40-7
1-(4-methylbenzyl)-1H-pyrrole

: 42867-34-5
1-((4-methylphenyl)methyl)-1H-pyrrole-2,5-dione

: C₁₂H₁₃NO₂

: C₁₄H₁₇NO₂

Guidance literature:: With rose bengal; oxygen; for 1h; Irradiation;
DOI:10.1039/c6ob01719c

Reference yield:

: 104-87-0
4-methyl-benzaldehyde

: 42867-34-5
1-((4-methylphenyl)methyl)-1H-pyrrole-2,5-dione

Guidance literature:: Multi-step reaction with 3 steps

1.1: hydroxylamine hydrochloride; sodium carbonate / ethanol / 20 °C

2.1: palladium 10% on activated carbon; hydrogen / ethanol / 20 °C

3.1: diethyl ether / 1 h / 20 °C

3.2: 6 h / 70 °C

With palladium 10% on activated carbon; hydroxylamine hydrochloride; hydrogen; sodium carbonate; In diethyl ether; ethanol;
DOI:10.1039/c2ob26699g