Guanylurea

Base Information

• Chemical Name: Guanylurea
• CAS No.: 141-83-3
• Deprecated CAS: 10310-28-8,36739-56-7,1608481-20-4,2242107-54-4
• Molecular Formula: C2H6 N4 O
• Molecular Weight: 102.096
• European Community (EC) Number: 205-504-6
• UNII: 128C2R3P8G
• DSSTox Substance ID: DTXSID3043811
• Nikkaji Number: J5.806H
• Wikidata: Q27251388
• Mol file: 141-83-3.mol

Synonyms:amidinourea;guanidine carboxamide;guanidine carboxamide phosphate;guanidine carboxamide, monohydrobromide;guanidine carboxamide, monohydrochloride;guanidine carboxamide, monohydroiodide;guanidine carboxamide, sulfate (1:1);guanidine carboxamide, sulfate (2:1);guanylurea

Chemical Property of Guanylurea

Chemical Property:

• Vapor Pressure: 0.000331mmHg at 25°C
• Melting Point: 173-175°C
• Refractive Index: 1.4164 (estimate)
• Boiling Point: 319.8°Cat760mmHg
• PKA: pK1:1.8;pK2:8.2 (25°C)
• Flash Point: 147.2°C
• PSA: 104.99000
• Density: 1.8g/cm³
• LogP: 0.43940
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility.: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
• XLogP3: -1.4
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 102.05416083
• Heavy Atom Count: 7
• Complexity: 102

Purity/Quality:

99% ^*data from raw suppliers

Guanylurea ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(=NC(=O)N)(N)N
• Uses: Guanylurea is used for detecting and determining Ni and its separation from Co and other metals.

Technology Process of Guanylurea

There total 45 articles about Guanylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

N-Cyanoguanidine (127099-85-8,780722-26-1,461-58-5) → carbamimidoylurea (141-83-3)

Guidance literature:

With hydrogenchloride; at 20 ℃; for 1.33333h;

DOI:10.1248/cpb.48.1504

Reference yield: 42.0%

N-Cyanoguanidine (127099-85-8,780722-26-1,461-58-5) → 2,4-diamino-6-guanidino-1,3,5-triazine (4405-08-7) + carbamimidoylurea (141-83-3) + 2,4,6-triguanidino-1,3,5-triazine (32151-75-0) + guanidine nitrate (113-00-8)

Guidance literature:

With hydrogenchloride; In N,N-dimethyl-formamide; at 80 ℃; for 0.5h;

DOI:10.1246/bcsj.58.2735

Reference yield:

CYANAMID (420-04-2) + sulfuric acid (7664-93-9) → carbamimidoylurea (141-83-3) + N-Cyanoguanidine (127099-85-8,780722-26-1,461-58-5) + urea (57-13-6)

Guidance literature:

bei ueberschuessiger Schwefelsaeure;

upstream raw materials:

potassium cyanate

guanidine hydrochloride

calcium cyanamide

N-carbamoylguanidinium nitrate

Downstream raw materials:

diethylbarbituric acid

5-amino-2-phenyl-1,2-dihydro-[1,2,4]triazol-3-one

2-thiobiuret

urea

Refernces

• 1、 Hatanaka, Masashi. "Anionic amidinourea-metal(II) tautomers: MN2O2or MN4?". . p. 162 - 172. Retrieved 2015.
• 2、 Sawant,Patil,Gokavi. "Kinetics and mechanism of oxidation of metformin hydrochloride by hexamolybdocobaltate(III) in acidic medium". . p. 15 - 20. Retrieved 2021/01/06.