2-Ethoxy-3-methoxybenzaldehyde

Base Information

• Chemical Name: 2-Ethoxy-3-methoxybenzaldehyde
• CAS No.: 66799-97-1
• Molecular Formula: C10H12O3
• Molecular Weight: 180.203
• European Community (EC) Number: 266-483-7
• NSC Number: 72388
• UNII: VL8L5E3XPH
• DSSTox Substance ID: DTXSID50216917
• Nikkaji Number: J310.152E
• Wikidata: Q83093234
• Mol file: 66799-97-1.mol

Synonyms:2-Ethoxy-3-methoxybenzaldehyde;66799-97-1;2-Ethoxy-m-anisaldehyde;Benzaldehyde, 2-ethoxy-3-methoxy-;VL8L5E3XPH;2-Ethoxy-3-methoxy-benzaldehyde;EINECS 266-483-7;MFCD00016584;NSC-72388;AI3-21326;NSC72388;UNII-VL8L5E3XPH;NCIOpen2_000589;SCHEMBL1125257;DTXSID50216917;BBL015362;NSC 72388;STK415414;2-Ethoxy-3-methoxybenzaldehyde, 98%;AKOS000271107;VS-04928;A8986;BB 0243260;CS-0312967;FT-0641093

Chemical Property of 2-Ethoxy-3-methoxybenzaldehyde

Chemical Property:

• Vapor Pressure: 0.00336mmHg at 25°C
• Refractive Index: n20/D 1.536(lit.)
• Boiling Point: 140 °C15 mm Hg(lit.)
• Flash Point: >230 °F
• PSA: 35.53000
• Density: 1.11 g/mL at 25 °C(lit.)
• LogP: 1.90640
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 180.078644241
• Heavy Atom Count: 13
• Complexity: 158

Purity/Quality:

97% ^*data from raw suppliers

2-Ethoxy-3-methoxybenzaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC1=C(C=CC=C1OC)C=O

Technology Process of 2-Ethoxy-3-methoxybenzaldehyde

There total 3 articles about 2-Ethoxy-3-methoxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diethyl sulfate (64-67-5) + 3-methoxy-2-hydroxybenzaldehyde (148-53-8) → 2-ethoxy-3-methoxybenzaldehyde (66799-97-1)

Guidance literature:

With sodium hydroxide; 2-methoxy-ethanol;

DOI:10.1021/jo01138a009

Reference yield:

3-methoxy-2-hydroxybenzaldehyde (148-53-8) + ethyl iodide (75-03-6) → 2-ethoxy-3-methoxybenzaldehyde (66799-97-1)

Guidance literature:

With sodium hydroxide;

Reference yield:

→ 2-ethoxy-3-methoxybenzaldehyde (66799-97-1)

Guidance literature:

o-vanilline, (CH3CH2)2SO4, anh. K2CO3, DMF;

DOI:10.1248/cpb.26.514

upstream raw materials:

diethyl sulfate

3-methoxy-2-hydroxybenzaldehyde

ethyl iodide

Downstream raw materials:

2-Nitro-1-(3-methoxy-2-ethoxy-phenyl)-propanol-⁽¹⁾

2-Ethoxy-3-methoxy-4'-cyan-chalkon

1,5-Bis-[(E)-2-(2-ethoxy-3-methoxy-phenyl)-vinyl]-2,4-dinitro-benzene

2-ethoxy-3-methoxy-6-nitro-benzaldehyde