1-((3,4-Dihydro-2H-1-benzopyran-2-yl)methyl)-4-phenylpiperazine

Base Information

Chemical Name:1-((3,4-Dihydro-2H-1-benzopyran-2-yl)methyl)-4-phenylpiperazine
CAS No.:81816-82-2
Molecular Formula:C₂₀H₂₄N₂O
Molecular Weight:308.423
Hs Code.:
DSSTox Substance ID:DTXSID101002244
Mol file:81816-82-2.mol

Synonyms:BRN 4534912;81816-82-2;1-((3,4-Dihydro-2H-1-benzopyran-2-yl)methyl)-4-phenylpiperazine;Piperazine, 1-((3,4-dihydro-2H-1-benzopyran-2-yl)methyl)-4-phenyl-;1-[(3,4-Dihydro-2H-1-benzopyran-2-yl)methyl]-4-phenylpiperazine;DTXSID101002244;LS-111547

Suppliers and Price of 1-((3,4-Dihydro-2H-1-benzopyran-2-yl)methyl)-4-phenylpiperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 1-((3,4-Dihydro-2H-1-benzopyran-2-yl)methyl)-4-phenylpiperazine

Chemical Property:

Vapor Pressure:1.36E-08mmHg at 25°C
Boiling Point:458.6°C at 760 mmHg
Flash Point:134.1°C
PSA：15.71000
Density:1.126g/cm³
LogP:3.20530
XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:308.188863393
Heavy Atom Count:23
Complexity:361

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=CC=CC=C2OC1CN3CCN(CC3)C4=CC=CC=C4

Technology Process of 1-((3,4-Dihydro-2H-1-benzopyran-2-yl)methyl)-4-phenylpiperazine

There total 5 articles about 1-((3,4-Dihydro-2H-1-benzopyran-2-yl)methyl)-4-phenylpiperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 81816-78-6
Chroman-2-yl-(4-phenyl-piperazin-1-yl)-methanone

: 81816-82-2
N¹-(2'-aminomethylchromanyl)-N⁴-phenylpiperazine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 6h; Heating;

Reference yield:

: 4940-39-0
acide chromone carboxylique-2

: 81816-82-2
N¹-(2'-aminomethylchromanyl)-N⁴-phenylpiperazine

Guidance literature:: Multi-step reaction with 4 steps

1: 75 percent / hydrogene / Pd/C / acetic acid / 70 °C

2: thionyl chloride / CHCl₃ / 3 h / Heating

3: 90 percent / triethylamine / benzene / 24 h

4: 50 percent / LAH / tetrahydrofuran / 6 h / Heating

With lithium aluminium tetrahydride; thionyl chloride; hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; chloroform; acetic acid; benzene;

Reference yield:

: 92-54-6
4-phenyl-1-piperazine

: 81816-82-2
N¹-(2'-aminomethylchromanyl)-N⁴-phenylpiperazine

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / triethylamine / benzene / 24 h

2: 50 percent / LAH / tetrahydrofuran / 6 h / Heating

With lithium aluminium tetrahydride; triethylamine; In tetrahydrofuran; benzene;