2-Chloro-4,6-diphenoxy-1,3,5-triazine

Base Information

• Chemical Name: 2-Chloro-4,6-diphenoxy-1,3,5-triazine
• CAS No.: 2972-65-8
• Molecular Formula: C15H10 Cl N3 O2
• Molecular Weight: 299.716
• Hs Code.: 2933699090
• NSC Number: 76483
• DSSTox Substance ID: DTXSID40274602
• Nikkaji Number: J33.214C
• Wikidata: Q82003992
• Mol file: 2972-65-8.mol

Synonyms:2-chloro-4,6-diphenoxy-1,3,5-triazine;2972-65-8;2,4-Diphenoxy-6-chloro-1,3,5-triazine;NSC76483;NCIOpen2_004073;SCHEMBL49317;DTXSID40274602;WPAYYYDSSCOEHN-UHFFFAOYSA-N;2,4-diphenoxy-6-chloro-s-triazine;NSC-76483;STL378505;AKOS000414584;1,5-Triazine, 2-chloro-4,6-diphenoxy-;2-chloro-4,6-diphenoxy-1,3,5-tri-azine;2-CHLORO-4,6-DIPHENOXY-S-TRIAZINE;1,3,5-Triazine, 2-chloro-4,6-diphenoxy-;2,4-bis(phenoxy)-6-chloro-1,3,5-triazine

Chemical Property of 2-Chloro-4,6-diphenoxy-1,3,5-triazine

Chemical Property:

• Vapor Pressure: 6.54E-09mmHg at 25°C
• Boiling Point: 480°C at 760 mmHg
• Flash Point: 244.1°C
• PSA: 57.13000
• Density: 1.348g/cm³
• LogP: 4.10960
• XLogP3: 4.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 299.0461543
• Heavy Atom Count: 21
• Complexity: 281

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)OC2=NC(=NC(=N2)Cl)OC3=CC=CC=C3

Technology Process of 2-Chloro-4,6-diphenoxy-1,3,5-triazine

There total 10 articles about 2-Chloro-4,6-diphenoxy-1,3,5-triazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.2%

1,3,5-trichloro-2,4,6-triazine (108-77-0) + phenol (108-95-2,27073-41-2) → 2,4-diphenoxy-6-chloro-s-triazine (2972-65-8)

Guidance literature:

With sodium hydroxide; In water; acetone; at 10 - 30 ℃; for 8h;

Reference yield: 92.6%

2,4-dichloro-6-phenoxy-1,3,5-triazine (4682-78-4) + phenol (108-95-2,27073-41-2) → 2,4-diphenoxy-6-chloro-s-triazine (2972-65-8)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 3h;

DOI:10.1021/acs.orglett.9b02878

Reference yield: 82.0%

1,3,5-trichloro-2,4,6-triazine (108-77-0) + phenol (108-95-2,27073-41-2) → α,α'-bis(p-methylphenyl)α,α'-bis(2,4-dipiperidino-1,3,5-triazine)succinonitrile + 2,4-diphenoxy-6-chloro-s-triazine (2972-65-8)

Guidance literature:

With sodium hydroxide; In water; acetone;

upstream raw materials:

1,3,5-trichloro-2,4,6-triazine

phenol

2,4-dichloro-6-(4-chlorophenoxy)-1,3,5-triazine

4-chloro-phenol

Downstream raw materials:

Benzoic acid 4,6-diphenoxy-[1,3,5]triazin-2-yl ester

2-[4-(4,6-Diphenoxy-[1,3,5]triazin-2-yl)-piperazin-1-yl]-6,7-dimethoxy-quinazolin-4-ylamine

2-piperidyl-4,6-diphenoxy-1,3,5-triazine

2-(carbazol-9'-yl)-4,6-bisphenoxy-1,3,5-triazine