2-Phenyl-N'-(phenylacetyl)acetohydrazide

Base Information

• Chemical Name: 2-Phenyl-N'-(phenylacetyl)acetohydrazide
• CAS No.: 793-25-9
• Molecular Formula: C16H16N2O2
• Molecular Weight: 268.315
• NSC Number: 42953
• DSSTox Substance ID: DTXSID501000383
• Nikkaji Number: J1.113.425D
• Wikidata: Q82993948
• ChEMBL ID: CHEMBL1325140
• Mol file: 793-25-9.mol

Synonyms:2-Phenyl-N'-(phenylacetyl)acetohydrazide;MLS000711330;2-phenyl-N'-(2-phenylacetyl)acetohydrazide;Phenyl-acetic acid N'-phenylacetyl-hydrazide;1,2-Bis(phenylacetyl)hydrazine;SMR000281097;793-25-9;SR-01000739698-2;diPhAcOH hydr;NSC42953;Opera_ID_1632;CBDivE_002245;cid_238532;SCHEMBL7107935;CHEMBL1325140;BDBM67470;DTXSID501000383;HMS2640O20;NSC-42953;STK107977;AKOS000583943;CCG-239680;2-Phenyl-N'-(phenylacetyl)acetohydrazide #;2-phenyl-N''-(2-phenylacetyl)acetohydrazide;2-phenyl-N''-(2-phenylethanoyl)ethanehydrazide;N''-(1-oxo-2-phenylethyl)-2-phenylacetohydrazide;N-(1-Hydroxy-2-phenylethylidene)-2-phenylethanehydrazonic acid

Chemical Property of 2-Phenyl-N'-(phenylacetyl)acetohydrazide

Chemical Property:

• XLogP3: 2.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 268.121177757
• Heavy Atom Count: 20
• Complexity: 286

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CC(=O)NNC(=O)CC2=CC=CC=C2

Technology Process of 2-Phenyl-N'-(phenylacetyl)acetohydrazide

There total 14 articles about 2-Phenyl-N'-(phenylacetyl)acetohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

2-phenylacetylhydrazine (937-39-3) → 1,2-di(phenylacetyl)hydrazine (793-25-9)

Guidance literature:

With Oxone; at 20 ℃; for 0.5h;

Reference yield: 86.0%

Ethyl α-diphenylphosphinylphenylacetate (66407-91-8) → 1,2-di(phenylacetyl)hydrazine (793-25-9) + diphenylphosphinic acid hydrazide (6779-66-4)

Guidance literature:

With hydrazine; at 125 - 130 ℃; for 12h;

Reference yield: 80.0%

benzeneseleninic acid (6996-92-5) + 2-phenylacetylhydrazine (937-39-3) → 1,2-di(phenylacetyl)hydrazine (793-25-9)

Guidance literature:

In chloroform; for 1h;

DOI:10.1021/jo00321a008

upstream raw materials:

chloroform

1-methyl-4-nitrosobenzene

thiosemicarbazide

phenylacetyl chloride

Downstream raw materials:

t-butyl phenylacetate

1,2-dimethyl-3-benzyl-4-phenyl-5-pyrazolone

N,N'-dimethyl-threo-2,3-diphenylsuccinimide

N,N'-dimethyl-N,N'-di(phenylacetyl)hydrazine