6-Fluoroveratraldehyde

Base Information

Chemical Name:6-Fluoroveratraldehyde
CAS No.:71924-62-4
Molecular Formula:C9H9FO3
Molecular Weight:184.167
Hs Code.:29122900
Mol file:71924-62-4.mol

Synonyms:2-Fluoro-4,5-dimethoxybenzaldehyde;4,5-Dimethoxy-2-fluorobenzaldehyde;6-Fluoroveratraldehyde;

Suppliers and Price of 6-Fluoroveratraldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Fluoro-4,5-dimethoxybenzaldehyde
100mg
$ 60.00

TCI Chemical
2-Fluoro-4,5-dimethoxybenzaldehyde >98.0%(GC)
5g
$ 119.00

TCI Chemical
2-Fluoro-4,5-dimethoxybenzaldehyde >98.0%(GC)
1g
$ 42.00

SynQuest Laboratories
4,5-Dimethoxy-2-fluorobenzaldehyde
1 g
$ 37.00

Matrix Scientific
2-Fluoro-4,5-dimethoxybenzaldehyde
25g
$ 750.00

Matrix Scientific
2-Fluoro-4,5-dimethoxybenzaldehyde
5g
$ 215.00

Matrix Scientific
2-Fluoro-4,5-dimethoxybenzaldehyde
10g
$ 376.00

Chemenu
2-fluoro-4,5-dimethoxybenzaldehyde 95+%
25g
$ 375.00

Apolloscientific
4,5-Dimethoxy-2-fluorobenzaldehyde
1g
$ 23.00

AOBChem
4,5-Dimethoxy-2-fluorobenzaldehyde 97%
25g
$ 188.00

Total 37 raw suppliers

Chemical Property of 6-Fluoroveratraldehyde

Chemical Property:

Appearance/Colour:white to slightly yellow crystalline powder
Melting Point:93-97 °C(lit.)
Boiling Point:273.3 °C at 760 mmHg
Flash Point:115.5 °C
PSA：35.53000
Density:1.201 g/cm³
LogP:1.65540
Sensitive.:Air Sensitive

Purity/Quality:

97% ^*data from raw suppliers

2-Fluoro-4,5-dimethoxybenzaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Uses 6-Fluoroveratraldehyde is used in the preparation of 6-[18F]fluoroveratraldehyde via nucleophilic aromatic substitution by [18F]fluoride. It is also used in the preparation of key metabolites of 6-fluoro-DOPA.

Technology Process of 6-Fluoroveratraldehyde

There total 4 articles about 6-Fluoroveratraldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 4885-02-3
Dichloromethyl methyl ether

: 398-62-9
4-fluoroveratrole

: 71924-62-4
2-fluoro-4,5-dimethoxybenzaldehyde

Guidance literature:: With titanium tetrachloride; In dichloromethane; 0 deg C, 0.5 h; RT, 4.5 h;
DOI:10.1021/jm00118a019

Reference yield:

: 6315-89-5
3,4-dimethoxyaniline

: 71924-62-4
2-fluoro-4,5-dimethoxybenzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) fluoroboric acid, n-butyl nitrile / 1.) methanol, 0 deg C, 1 h, 2.) reflux

2: 60 percent / TiCl₄ / CH₂Cl₂ / 4.5 h

With tetrafluoroboric acid; propyl cyanide; titanium tetrachloride; In dichloromethane;
DOI:10.1021/jo00371a032

Reference yield:

: 120-14-9
3,4-dimethoxy-benzaldehyde

: 71924-62-4
2-fluoro-4,5-dimethoxybenzaldehyde

Guidance literature:: With acetyl hypofluorite; mercury(II) trifluoroacetate; Yield given. Multistep reaction; 1.) ethanol, room temperature, 72 h, 2.) CHCl₃/freon, room temperature;
DOI:10.1016/S0040-4039(00)80335-4