Sufentanil

Base Information Edit

Chemical Name:Sufentanil
CAS No.:56030-54-7
Molecular Formula:C22H30 N2 O2 S
Molecular Weight:386.558
Hs Code.:
European Community (EC) Number:641-081-8
UNII:AFE2YW0IIZ
DSSTox Substance ID:DTXSID6023604
Nikkaji Number:J11.105H
Wikipedia:Sufentanil
Wikidata:Q417915
NCI Thesaurus Code:C61956
RXCUI:56795
Pharos Ligand ID:ZPDYKMXTKK3N
Metabolomics Workbench ID:43016
ChEMBL ID:CHEMBL658
Mol file:56030-54-7.mol

Synonyms:Citrate, Sufentanil;Curasan, Sufentanil;R 30730;R-30730;R30730;Sufenta;Sufentanil;Sufentanil Citrate;Sufentanil curasan;Sufentanil Hameln;Sufentanil Ratiopharm;Sufentanil-hameln;Sufentanil-ratiopharm;SufentanilHameln;SufentanilRatiopharm;Sulfentanil;Sulfentanyl

This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of Sufentanil Edit

Chemical Property:

Vapor Pressure:7.23E-10mmHg at 25°C
Melting Point:103-104℃
Boiling Point:493.1°Cat760mmHg
PKA:7.89±0.20(Predicted)
Flash Point:252°C
PSA：61.02000
Density:1.132g/cm³
LogP:4.15270
Storage Temp.:2-8°C
Solubility.:Practically insoluble in water, freely soluble in ethanol (96 per cent) and in methanol.
Water Solubility.:76mg/L(25 oC)
XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:386.20279938
Heavy Atom Count:27
Complexity:459

Purity/Quality:

Safty Information:

Pictogram(s): F,T
Hazard Codes:F,T
Statements: 11-23/24/25-39/23/24/25
Safety Statements: 7-16-36/37-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCC3=CC=CS3)COC
Recent ClinicalTrials:Intraoperative Methadone Administration for Improved Pain Control in Spinal Fusion Patients
Recent EU Clinical Trials:a Randomized controlled trial for epidural Analgesia for Pain relief after lumbar Interlaminar Decompressive spine surgery - RAPID
Recent NIPH Clinical Trials:Effects of intravenous administration of magnesium sulfate in propofol-based sedation for ERCP in elderly patients: a randomized, double-blind, placebo-controlled study
Description Sufentanil is a narcotic analgesic with a greater potency and therapeutic ratio than its structural relative fentanyl. It appears to produce fewer cardiac effects and less respiratory depression than fentanyl, and thus is especially useful as an analgesic/anesthetic in open heart surgery. Sufentanil (Item No. 15917) is an analytical reference material categorized as an opioid. Sufentanil is regulated as a Schedule II compound in the United States. This product is intended for research and forensic applications.
Uses Opioid receptor agonist; analgesic.
Therapeutic Function Analgesic

Technology Process of Sufentanil

There total 17 articles about Sufentanil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.5%