Nafoxidine

Base Information

Chemical Name:Nafoxidine
CAS No.:1845-11-0
Molecular Formula:C29H31 N O2
Molecular Weight:425.571
Hs Code.:2933990090
European Community (EC) Number:694-510-6
UNII:4RIY10WM82
DSSTox Substance ID:DTXSID7022386
Nikkaji Number:J7.793C
Wikipedia:Nafoxidine
Wikidata:Q6958201
NCI Thesaurus Code:C677
Pharos Ligand ID:DN5D1HRUZWNA
Metabolomics Workbench ID:67476
ChEMBL ID:CHEMBL28211
Mol file:1845-11-0.mol

Synonyms:Hydrochloride, Nafoxidine;Nafoxidine;Nafoxidine Hydrochloride;U 11,100A;U 11000A;U-11,100A;U-11000A;U11,100A;U11000A

Suppliers and Price of Nafoxidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
NAFOXIDINE 95.00%
5MG
$ 499.96

Total 33 raw suppliers

Chemical Property of Nafoxidine

Chemical Property:

Refractive Index:1.6290 (estimate)
Boiling Point:574.5°Cat760mmHg
Flash Point:176.7°C
PSA：21.70000
Density:1.137g/cm³
LogP:6.01300
XLogP3:5.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:425.235479232
Heavy Atom Count:32
Complexity:611

Purity/Quality:

99% ^*data from raw suppliers

NAFOXIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)C(=C(CC2)C3=CC=CC=C3)C4=CC=C(C=C4)OCCN5CCCC5
Uses Anti-estrogen.

Technology Process of Nafoxidine

There total 11 articles about Nafoxidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 123-75-1
pyrrolidine

: 1449689-98-8
4-[4-(2-chloro-ethoxy)-phenyl]-7-methoxy-3-phenyl-1,2-dihydro-naphthalene

: 1845-11-0
nafoxidine

Guidance literature:: In ethanol; at 100 ℃; for 4h; Inert atmosphere; Sealed tube;
DOI:10.1021/ja405972h

Reference yield: 82.0%

: 5050-41-9
N-(2-chloroethyl)-pyrrolidine

: 1729-38-0
1-(p-hydroxyphenyl)-6-methoxy-2-phenyl-3,4-dihydronaphthalene

: 1845-11-0
nafoxidine

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; at 50 ℃;
DOI:10.1246/cl.2007.40

Reference yield: 82.0%

: 1729-38-0
1-(p-hydroxyphenyl)-6-methoxy-2-phenyl-3,4-dihydronaphthalene

: 7250-67-1
1-(2-chloroethyl)pyrrolidine hydrochloride

: 1845-11-0
nafoxidine

Guidance literature:: 1-(p-hydroxyphenyl)-6-methoxy-2-phenyl-3,4-dihydronaphthalene; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 0.333333h;

1-(2-chloroethyl)pyrrolidine hydrochloride; In N,N-dimethyl-formamide; at 50 ℃; for 11h;