1-Cyclopropyl-1-nitrosourea

Base Information

• Chemical Name: 1-Cyclopropyl-1-nitrosourea
• CAS No.: 10575-90-3
• Molecular Formula: C4H7 N3 O2
• Molecular Weight: 129.118
• DSSTox Substance ID: DTXSID50147313
• Nikkaji Number: J59.454G
• Wikidata: Q83012580
• Mol file: 10575-90-3.mol

Synonyms:1-Cyclopropyl-1-nitrosourea;N-Nitroso-N-cyclopropylurea;Urea, 1-cyclopropyl-1-nitroso-;BRN 1818031;Urea, N-cyclopropyl-N-nitroso-;10575-90-3;3-12-00-00004 (Beilstein Handbook Reference);N-cyclopropyl-N-nitrosourea;SCHEMBL21753529;DTXSID50147313;AKOS006341337;LS-159719

Chemical Property of 1-Cyclopropyl-1-nitrosourea

Chemical Property:

• Vapor Pressure: 0.0975mmHg at 25°C
• Boiling Point: 223.2°C at 760 mmHg
• Flash Point: 88.8°C
• Density: 1.72g/cm³
• XLogP3: 0
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 129.053826475
• Heavy Atom Count: 9
• Complexity: 143

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC1N(C(=O)N)N=O

Technology Process of 1-Cyclopropyl-1-nitrosourea

There total 1 articles about 1-Cyclopropyl-1-nitrosourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.2%

1-cyclopropylurea (19757-64-3) → N-nitroso-N-cyclopropylurea (10575-90-3)

Guidance literature:

With hydrogenchloride; sodium nitrite; In water; at 0 ℃; for 1h;

Reference yield: 17.0%

N-nitroso-N-cyclopropylurea (10575-90-3) + phenol (108-95-2,27073-41-2) → 4-(cyclopropyldiazenyl)phenol + 2-allyl-4-(cyclopropyldiazenyl)phenol + allyl phenyl ether (1746-13-0) + o-Allylphenol (1745-81-9)

Guidance literature:

With caesium carbonate; In dichloromethane; at 5 - 8 ℃; for 0.833333h; Further byproducts given;

DOI:10.1134/S1070428006090089

Reference yield:

oxirane (75-21-8,99932-75-9) + methanol (67-56-1) + N-nitroso-N-cyclopropylurea (10575-90-3) → methylallylether (627-40-7) + monoethylene glycol methyl allyl ether (18854-48-3,27252-80-8) + cyclopropyl methyl ether (540-47-6) + 3-<2-(2-Methoxyethoxy)ethoxy>propen (13752-97-1,27252-80-8) + (2-Methoxyethoxy)cyclopropan

Guidance literature:

With sodium hydrogencarbonate; Product distribution; Ambient temperature; var. conc., further reactions with NaOCH₃, oxetane, tetrahydrofuran;

upstream raw materials:

1-cyclopropylurea

Downstream raw materials:

allyl alcohol

methylallylether

monoethylene glycol methyl allyl ether

cyclopropyl methyl ether

Refernces