4-(4-Methoxyphenyl)-3-phenoxyazetidin-2-one

Base Information

Chemical Name:4-(4-Methoxyphenyl)-3-phenoxyazetidin-2-one
CAS No.:101067-53-2
Molecular Formula:C16H15NO3
Molecular Weight:269.29500
Hs Code.:
DSSTox Substance ID:DTXSID30540686
Mol file:101067-53-2.mol

Synonyms:4-(4-methoxyphenyl)-3-phenoxyazetidin-2-one;101067-53-2;DTXSID30540686;AKOS015907278;4-(4-methoxyphenyl)-3-phenoxy-2-azetidinone

Suppliers and Price of 4-(4-Methoxyphenyl)-3-phenoxyazetidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of 4-(4-Methoxyphenyl)-3-phenoxyazetidin-2-one

Chemical Property:

PSA：51.05000
LogP:2.58960
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:269.10519334
Heavy Atom Count:20
Complexity:333

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2C(C(=O)N2)OC3=CC=CC=C3

Technology Process of 4-(4-Methoxyphenyl)-3-phenoxyazetidin-2-one

There total 40 articles about 4-(4-Methoxyphenyl)-3-phenoxyazetidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: C₂₄H₂₃NO₄

: 50899-71-3,101067-53-2
(3S,4R)-4-(4-Methoxy-phenyl)-3-phenoxy-azetidin-2-one

: 10021-55-3
sodium 2,5-dihydroxybenzenesulfonate

Guidance literature:: With cerium(IV) ammonium nitrate; silica gel; In dichloromethane; for 0.25h;
DOI:10.1055/s-2008-1032051

Reference yield: 85.0%

: C₂₄H₂₃NO₄

: 50899-71-3,101067-53-2
(3S,4R)-4-(4-Methoxy-phenyl)-3-phenoxy-azetidin-2-one

: 106-51-4
p-benzoquinone

Guidance literature:: With cerium(IV) ammonium nitrate; silica gel; In dichloromethane; at 20 ℃;
DOI:10.1055/s-2008-1032051

Reference yield: 85.0%

: 123-11-5
4-methoxy-benzaldehyde

: 701-99-5
Phenoxyacetyl chloride

: 50899-71-3,101067-53-2
cis-4-(4-methoxyphenyl)-3-phenoxy-azetidin-2-one

Guidance literature:: 4-methoxy-benzaldehyde; With p-benzyloxyaniline resine; In dichloromethane; at 20 ℃; for 0.5h;

Phenoxyacetyl chloride; With triethylamine; In dichloromethane; at 20 ℃; for 18h;

With ammonium cerium(IV) nitrate; In water; acetonitrile; at 20 ℃; for 0.5h; Further stages.;
DOI:10.1021/ol006766l