1,1,2,2-Cyclopropanetetracarboxylic acid, 3-phenyl-, tetramethyl ester

Base Information

• Chemical Name: 1,1,2,2-Cyclopropanetetracarboxylic acid, 3-phenyl-, tetramethyl ester
• CAS No.: 101595-78-2
• Molecular Formula: C17H18O8
• Molecular Weight: 350.325
• Mol file: 101595-78-2.mol

Synonyms:3-phenyl-1,1,2,2-tetramethoxycarbonylcyclopropane;3-phenyl-cyclopropane-1,1,2,2-tetracarboxylic acid tetramethyl ester;1,1,2,2-Cyclopropanetetracarboxylic acid,3-phenyl-,tetramethyl ester;tetramethyl ester of 3-phenylcyclopropane-1,1,2,2-tetracarboxylic acid;3-Phenyl-cyclopropan-1,1,2,2-tetracarbonsaeure-tetramethylester;

Chemical Property of 1,1,2,2-Cyclopropanetetracarboxylic acid, 3-phenyl-, tetramethyl ester

Chemical Property:

• PSA: 105.20000
• LogP: 0.44860

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,1,2,2-Cyclopropanetetracarboxylic acid, 3-phenyl-, tetramethyl ester

There total 8 articles about 1,1,2,2-Cyclopropanetetracarboxylic acid, 3-phenyl-, tetramethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-phenyl-propane-1,1,3,3-tetracarboxylic acid tetramethyl ester (5619-82-9) → tetramethyl ester of 3-phenylcyclopropane-1,1,2,2-tetracarboxylic acid (101595-78-2)

Guidance literature:

With sodium iodide; In methanol; at 30 ℃; electrolysis (Pt vs. Fe) with current density of 220 mA/cm², amount 2F;

DOI:10.1007/BF01184531

Reference yield: 67.0%

Benzylidenemalononitrile (2700-22-3) + malonic acid dimethyl ester (108-59-8) → tetramethyl ester of 3-phenylcyclopropane-1,1,2,2-tetracarboxylic acid (101595-78-2)

Guidance literature:

With Pyridine hydrobromide; In acetonitrile; at 20 ℃; Electrochemical reaction; Electrolysis;

DOI:10.1016/j.mencom.2019.07.010

Reference yield:

dimethyl 2-benzylidenepropanedioate (6626-84-2) + methyl 2-cyanoacetate (105-34-0) → tetramethyl meso-2,3-diphenylbutane-1,1,4,4-tetracarboxylate (142560-17-6) + tetramethyl ester of 3-phenylcyclopropane-1,1,2,2-tetracarboxylic acid (101595-78-2) + trimethyl(2R*,3R*)-2-cyano-3-phenylcyclopropane-1,1,2-tricarboxylate

Guidance literature:

With sodium bromide; In methanol; at -20 ℃; Electrochemical reaction;

DOI:10.1016/j.tet.2006.02.027

upstream raw materials:

2-phenyl-propane-1,1,3,3-tetracarboxylic acid tetramethyl ester

dimethyl 2-benzylidenepropanedioate

methyl 2-cyanoacetate

benzaldehyde