Benzoic acid, 4-[(3-oxo-1,3-diphenylpropyl)amino]-, ethyl ester

Base Information

• Chemical Name: Benzoic acid, 4-[(3-oxo-1,3-diphenylpropyl)amino]-, ethyl ester
• CAS No.: 102951-07-5
• Molecular Formula: C24H23NO3
• Molecular Weight: 373.44400
• DSSTox Substance ID: DTXSID40387887
• Nikkaji Number: J1.789.995C
• Mol file: 102951-07-5.mol

Synonyms:102951-07-5;Benzoic acid, 4-[(3-oxo-1,3-diphenylpropyl)amino]-, ethyl ester;ethyl 4-[(3-oxo-1,3-diphenylpropyl)amino]benzoate;Oprea1_686874;DTXSID40387887;4-(alpha-Phenacylbenzylamino)benzoic acid ethyl ester;phenyl b-phenyl-b-[p-(ethoxy-carbonyl)phenylamino]ethyl ketone

Chemical Property of Benzoic acid, 4-[(3-oxo-1,3-diphenylpropyl)amino]-, ethyl ester

Chemical Property:

• PSA: 55.40000
• LogP: 5.36250
• XLogP3: 5.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 9
• Exact Mass: 373.16779360
• Heavy Atom Count: 28
• Complexity: 486

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C1=CC=C(C=C1)NC(CC(=O)C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of Benzoic acid, 4-[(3-oxo-1,3-diphenylpropyl)amino]-, ethyl ester

There total 4 articles about Benzoic acid, 4-[(3-oxo-1,3-diphenylpropyl)amino]-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

1-styrenyloxytrimethylsilane (13735-81-4) + benzylidene[p-(ethoxycarbonyl)phenyl]amine (7182-99-2) → phenyl β-phenyl-β-[p-(ethoxycarbonyl)phenylamino]ethyl ketone (102951-07-5)

Guidance literature:

With tetrafluoroboric acid; In methanol; for 1h;

DOI:10.1002/1615-4169(200206)344:3/4<338::AID-ADSC338>3.0.CO;2-O

Reference yield: 91.0%

benzaldehyde (100-52-7) + acetophenone (98-86-2) + p-aminoethylbenzoate (94-09-7) → phenyl β-phenyl-β-[p-(ethoxycarbonyl)phenylamino]ethyl ketone (102951-07-5)

Guidance literature:

Yb(OSO₂C₈H₁₇)3; In toluene; at 60 ℃; for 10h;

DOI:10.1016/j.jfluchem.2006.07.009

Reference yield: 43.0%

benzylidene[p-(ethoxycarbonyl)phenyl]amine (7182-99-2) + acetophenone (98-86-2) → phenyl β-phenyl-β-[p-(ethoxycarbonyl)phenylamino]ethyl ketone (102951-07-5)

Guidance literature:

With hydrogenchloride; In ethanol; Heating;

DOI:10.1023/B:RUGC.0000042429.06729.93

upstream raw materials:

1-styrenyloxytrimethylsilane

benzylidene[p-(ethoxycarbonyl)phenyl]amine

acetophenone

benzaldehyde