1-Ethyl-2,3-dimethoxybenzene

Base Information

• Chemical Name: 1-Ethyl-2,3-dimethoxybenzene
• CAS No.: 103517-22-2
• Molecular Formula: C10H14O2
• Molecular Weight: 166.22
• DSSTox Substance ID: DTXSID00599560
• Nikkaji Number: J3.588.066F
• Wikidata: Q82495457
• Mol file: 103517-22-2.mol

Synonyms:1-ethyl-2,3-dimethoxybenzene;103517-22-2;Benzene, 1-ethyl-2,3-dimethoxy-;1-Ethyl-2,3-dimethoxy-benzene;dimethoxy ethylbenzene;SCHEMBL464374;DTXSID00599560

Chemical Property of 1-Ethyl-2,3-dimethoxybenzene

Chemical Property:

• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 166.099379685
• Heavy Atom Count: 12
• Complexity: 125

Purity/Quality:

≥99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC1=C(C(=CC=C1)OC)OC

Technology Process of 1-Ethyl-2,3-dimethoxybenzene

There total 7 articles about 1-Ethyl-2,3-dimethoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.8%

1-(2,3-dimethoxyphenyl)-1-ethanol (6848-73-3) → 3-ethyl-1,2-dimethoxybenzene (103517-22-2)

Guidance literature:

With hydrogen; palladium on activated charcoal; In acetic acid; for 6h; under 2844.3 Torr;

DOI:10.1002/mrc.1260250412

Reference yield: 75.0%

bis(iodozinc)methane (31729-70-1) + 2,3-dimethyoxybenzaldehyde (86-51-1) → 3-ethyl-1,2-dimethoxybenzene (103517-22-2)

Guidance literature:

With Wilkinson's catalyst; hydrogen; In tetrahydrofuran; at 25 ℃; for 48h; under 760.051 Torr; Temperature; Catalytic behavior;

DOI:10.1002/ejoc.201601137

Reference yield: 62.0%

nysted reagent + 2,3-dimethyoxybenzaldehyde (86-51-1) → 3-ethyl-1,2-dimethoxybenzene (103517-22-2)

Guidance literature:

With Wilkinson's catalyst; boron trifluoride diethyl etherate; hydrogen; In tetrahydrofuran; at -78 - 25 ℃; for 48h; under 760.051 Torr; Catalytic behavior;

DOI:10.1002/ejoc.201601137

upstream raw materials:

2,3-dimethoxyacetophenone

1-(2,3-dimethoxyphenyl)-1-ethanol

hydrogenchloride

dihydroxy-methyl-borane

Downstream raw materials:

2-ethyl-3,4-dimethoxybenzaldehyde

2-ethyl-1-chloromethyl-3,4-dimethoxy-benzene

8-ethyl-1,2-dihydro-6,7-dimethoxy-2-methyl-3-(phenylmethyl)naphthalene

8-ethyl-1,2-dihydro-6,7-dimethoxy-2-methyl-3-(4-methylphenylmethyl)naphthalene