2,6,8-Trimethyl-5-hydroxy-7-methoxychromone

Base Information

• Chemical Name: 2,6,8-Trimethyl-5-hydroxy-7-methoxychromone
• CAS No.: 478-47-7
• Molecular Formula: C13H14O4
• Molecular Weight: 0
• Mol file: 478-47-7.mol

Synonyms:5-Hydroxy-7-methoxy-2,6,8-trimethyl-chromen-4-one;Angustifolionol;5-Hydroxy-7-methoxy-2,6,8-trimethyl-chromen-4-on;

Chemical Property of 2,6,8-Trimethyl-5-hydroxy-7-methoxychromone

Chemical Property:

• PSA: 59.67000
• LogP: 2.43240

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,6,8-Trimethyl-5-hydroxy-7-methoxychromone

There total 6 articles about 2,6,8-Trimethyl-5-hydroxy-7-methoxychromone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5,7-dihydroxy-2,8-dimethylchromone (479-06-1) + methyl iodide (74-88-4) → 8-methyleugenitol (41682-21-7) + 5-hydroxy-7-methoxy-2,6,8-trimethylchromone (478-47-7)

Guidance literature:

With methanol; sodium methylate;

Reference yield:

methanol (67-56-1) + 5,7-dihydroxy-2,8-dimethylchromone (479-06-1) + sodium methylate (124-41-4) + methyl iodide (74-88-4) → 8-methyleugenitol (41682-21-7) + 5-hydroxy-7-methoxy-2,6,8-trimethylchromone (478-47-7)

Guidance literature:

Reference yield:

1-(2,4,6-trihydroxy-3,5-dimethylphenyl)ethan-1-one (13383-63-6) → 5-hydroxy-7-methoxy-2,6,8-trimethylchromone (478-47-7)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium acetate

2: aqueous sodium carbonate-solution

3: potassium carbonate; acetone

With sodium acetate; sodium carbonate; potassium carbonate; acetone;

upstream raw materials:

diazomethane

8-methyleugenitol

methanol

5,7-dihydroxy-2,8-dimethylchromone

Downstream raw materials:

2,6-dihydroxy-4-methoxy-3,5-dimethyl-benzoic acid

2,6-Dimethylphloroglucin-1-monomethylether