(S)-Benzyl (1-(Methoxy(Methyl)Amino)-4-Methyl-1-Oxopentan-2-Yl)Carbamate

Base Information

Chemical Name:(S)-Benzyl (1-(Methoxy(Methyl)Amino)-4-Methyl-1-Oxopentan-2-Yl)Carbamate
CAS No.:109075-73-2
Molecular Formula:C16H24N2O4
Molecular Weight:308.378
Hs Code.:
Mol file:109075-73-2.mol

Synonyms:[(S)-1-(Methoxy-methyl-carbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester;Z-Leu-N(OMe)Me;(S)-benzyl (1-(methoxy(methyl)amino)-4-methyl-1-oxopentan-2-yl)carbamate;Z-Leu N-methoxy-N-methyl amide;(S)-benzyl {1-[methoxy(methyl)amino]-4-methyl-1-oxopentan-2-yl}carbamate;N-Benzyloxycarbonyl-L-leucine (N-methyl-N-methoxy)amide;

Suppliers and Price of (S)-Benzyl (1-(Methoxy(Methyl)Amino)-4-Methyl-1-Oxopentan-2-Yl)Carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-Benzyl(1-(methoxy(methyl)amino)-4-methyl-1-oxopentan-2-yl)carbamate 97%
5g
$ 446.00

Total 2 raw suppliers

Chemical Property of (S)-Benzyl (1-(Methoxy(Methyl)Amino)-4-Methyl-1-Oxopentan-2-Yl)Carbamate

Chemical Property:

PKA:10.98±0.46(Predicted)
PSA：67.87000
Density:1.108±0.06 g/cm3(Predicted)
LogP:2.73820

Purity/Quality:

99% ^*data from raw suppliers

(S)-Benzyl(1-(methoxy(methyl)amino)-4-methyl-1-oxopentan-2-yl)carbamate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (S)-Benzyl (1-(Methoxy(Methyl)Amino)-4-Methyl-1-Oxopentan-2-Yl)Carbamate

There total 6 articles about (S)-Benzyl (1-(Methoxy(Methyl)Amino)-4-Methyl-1-Oxopentan-2-Yl)Carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 2018-66-8
Z-Leu-OH

: 6638-79-5
N,O-dimethylhydroxylamine*hydrochloride

: 109075-73-2
benzyl (S)-[1-(N-methoxy-N-methylamino)-4-methyl-1-oxopentan-2-yl]carbamate

Guidance literature:: Z-Leu-OH; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 0 ℃; for 0.25h;

N,O-dimethylhydroxylamine*hydrochloride; With 4-methyl-morpholine; In dichloromethane; at 0 - 20 ℃;
DOI:10.1016/j.bmc.2021.116459

Reference yield: 69.0%

: 2018-66-8
Z-Leu-OH

: 1117-97-1
N,0-dimethylhydroxylamine

: 109075-73-2
benzyl (S)-[1-(N-methoxy-N-methylamino)-4-methyl-1-oxopentan-2-yl]carbamate

Guidance literature:: With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide;
DOI:10.1016/S0960-894X(01)00755-7

Reference yield: 31.4%

: 2018-66-8
Z-Leu-OH

: N-methoxy-N-methylhydroxylamine

: 109075-73-2
benzyl (S)-[1-(N-methoxy-N-methylamino)-4-methyl-1-oxopentan-2-yl]carbamate

Guidance literature:: Z-Leu-OH; With 4-methyl-morpholine; 4 A molecular sieve; isobutyl chloroformate; In methanol; at -10 ℃; for 0.25h;

N-methoxy-N-methylhydroxylamine; Further stages.; cooling;
DOI:10.1021/ac0488558