(1Z)-2-diazonio-1-phenylprop-1-en-1-olate

Base Information

• Chemical Name: (1Z)-2-diazonio-1-phenylprop-1-en-1-olate
• CAS No.: 14088-57-4
• Molecular Formula: C9H8 N2 O
• Molecular Weight: 160.175
• Mol file: 14088-57-4.mol

Synonyms:1-Propanone,2-diazo-1-phenyl- (9CI); Propiophenone, 2-diazo- (6CI,7CI,8CI);1-Benzoyl-1-diazoethane; 2-Diazopropiophenone; a-Diazopropiophenone

Chemical Property of (1Z)-2-diazonio-1-phenylprop-1-en-1-olate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (1Z)-2-diazonio-1-phenylprop-1-en-1-olate

There total 10 articles about (1Z)-2-diazonio-1-phenylprop-1-en-1-olate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

Methanesulfonyl azide (624-90-8,1516-70-7) + 1-phenyl-propan-1-one (93-55-0) → 2-diazo-1-phenyl-1-propanone (14088-57-4)

Guidance literature:

1-phenyl-propan-1-one; With sodium hydride; formic acid ethyl ester; In diethyl ether; ethanol; mineral oil; at 0 - 20 ℃; for 15h; Inert atmosphere;

Methanesulfonyl azide; In diethyl ether; ethanol; mineral oil; for 2h; Inert atmosphere;

DOI:10.1021/acs.joc.6b02998

Reference yield: 63.0%

2-azido-1-phenyl-1-propanone (35947-99-0) → 2-diazo-1-phenyl-1-propanone (14088-57-4)

Guidance literature:

With pyrrolidine; toluene-4-sulfonic acid hydrazide; In dimethyl sulfoxide; at 25 ℃; for 0.5h; Inert atmosphere;

DOI:10.1021/acs.joc.8b02074

Reference yield: 60.0%

Diazoethan (1117-96-0) + benzoyl chloride (98-88-4) → 2-diazo-1-phenyl-1-propanone (14088-57-4)

Guidance literature:

In diethyl ether; at 0 ℃; for 2h;

DOI:10.1021/jo962271r

upstream raw materials:

Diazoethan

benzoyl chloride

2-benzoylpropanal

3-hydroxy-2-methyl-1-phenyl-2-propen-1-one

Downstream raw materials:

2-methoxy-1-phenyl-propan-1-one

2-ethoxy-1-phenyl-propan-1-one

Phenyl vinyl ketone

N-phenyl-2-phenylpropanamide