Technology Process of 1H-1,2,3-Triazolo[4,5-d]pyrimidin-1-amine,
5-(1,1-dimethylethyl)-N-(phenylmethylene)-
There total 8 articles about 1H-1,2,3-Triazolo[4,5-d]pyrimidin-1-amine,
5-(1,1-dimethylethyl)-N-(phenylmethylene)- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
acetic acid;
In
methanol;
for 72h;
Heating;
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 86 percent / aq. NaOH / Ambient temperature; overnight
2: 92 percent / KNO3, H2SO4 conc. / 8 h / 115 °C
3: POCl3 / 1) reflux, 3 h, 2) RT, overnight
4: aq. NH3 / 0 deg C - RT
5: H2 / 5percent Pd/C / methanol / Ambient temperature
6: NaNO2, aq. HCl / 1 h / 0 °C
7: 31 percent / 1) NaH, 2) aq. O-mesitylsulfonylhydroxylamine / 1) ether, 2) ether, RT, overnight; other base (10percent alcoholic KOH)
8: 40 percent / acetic acid / methanol / 72 h / Heating
With
hydrogenchloride; ammonium hydroxide; sodium hydroxide; sulfuric acid; hydrogen; mesitylenesulfonylhydroxylamine; sodium hydride; acetic acid; potassium nitrate; sodium nitrite; trichlorophosphate;
palladium on activated charcoal;
In
methanol;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: aq. NH3 / 0 deg C - RT
2: H2 / 5percent Pd/C / methanol / Ambient temperature
3: NaNO2, aq. HCl / 1 h / 0 °C
4: 31 percent / 1) NaH, 2) aq. O-mesitylsulfonylhydroxylamine / 1) ether, 2) ether, RT, overnight; other base (10percent alcoholic KOH)
5: 40 percent / acetic acid / methanol / 72 h / Heating
With
hydrogenchloride; ammonium hydroxide; hydrogen; mesitylenesulfonylhydroxylamine; sodium hydride; acetic acid; sodium nitrite;
palladium on activated charcoal;
In
methanol;