2-(Tert-butyl)-4-chloro-5-nitropyrimidine

Base Information

Chemical Name:2-(Tert-butyl)-4-chloro-5-nitropyrimidine
CAS No.:70227-50-8
Molecular Formula:C₈H₁₀ClN₃O₂
Molecular Weight:215.639
Hs Code.:
DSSTox Substance ID:DTXSID801237991
Mol file:70227-50-8.mol

Synonyms:2-(TERT-BUTYL)-4-CHLORO-5-NITROPYRIMIDINE;70227-50-8;2-TERT-BUTYL-4-CHLORO-5-NITROPYRIMIDINE;SCHEMBL10184980;DTXSID801237991;MFCD18250574;AKOS027254873;AB73257;BS-17949;CS-0154882;4-Chloro-2-(1,1-dimethylethyl)-5-nitropyrimidine;A1-01803

Suppliers and Price of 2-(Tert-butyl)-4-chloro-5-nitropyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Ambeed
2-(tert-Butyl)-4-chloro-5-nitropyrimidine 95%
250mg
$ 259.00

Ambeed
2-(tert-Butyl)-4-chloro-5-nitropyrimidine 95%
100mg
$ 174.00

Ambeed
2-(tert-Butyl)-4-chloro-5-nitropyrimidine 95%
1g
$ 672.00

Alichem
2-(Tert-butyl)-4-chloro-5-nitropyrimidine
1g
$ 1248.75

Alichem
2-(Tert-butyl)-4-chloro-5-nitropyrimidine
250mg
$ 450.00

Total 6 raw suppliers

Chemical Property of 2-(Tert-butyl)-4-chloro-5-nitropyrimidine

Chemical Property:

PSA：71.60000
LogP:2.85890
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:215.0461543
Heavy Atom Count:14
Complexity:224

Purity/Quality:

97% ^*data from raw suppliers

2-(tert-Butyl)-4-chloro-5-nitropyrimidine 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)C1=NC=C(C(=N1)Cl)[N+](=O)[O-]

Technology Process of 2-(Tert-butyl)-4-chloro-5-nitropyrimidine

There total 3 articles about 2-(Tert-butyl)-4-chloro-5-nitropyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 70227-49-5
2-tert-butyl-5-nitro-3H-pyrimidin-4-one

: 70227-50-8
4-chloro-5-nitro-2-t-butylpyrimidine

Guidance literature:: With trichlorophosphate; for 5h; Heating / reflux;

Reference yield:

: 18202-73-8
pivalamidine hydrochloride

: 70227-50-8
4-chloro-5-nitro-2-t-butylpyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1: 86 percent / aq. NaOH / Ambient temperature; overnight

2: 92 percent / KNO₃, H₂SO₄ conc. / 8 h / 115 °C

3: POCl₃ / 1) reflux, 3 h, 2) RT, overnight

With sodium hydroxide; sulfuric acid; potassium nitrate; trichlorophosphate;

Reference yield:

: 42351-88-2
2-t-butyl-3,4-dihydro-4-oxopyrimidine

: 70227-50-8
4-chloro-5-nitro-2-t-butylpyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / KNO₃, H₂SO₄ conc. / 8 h / 115 °C

2: POCl₃ / 1) reflux, 3 h, 2) RT, overnight

With sulfuric acid; potassium nitrate; trichlorophosphate;