3-Chloro-3,4-dihydro-3-phenyl-2(1H)-quinolinone

Base Information

Chemical Name:3-Chloro-3,4-dihydro-3-phenyl-2(1H)-quinolinone
CAS No.:113092-93-6
Molecular Formula:C15H12ClNO
Molecular Weight:257.719
Hs Code.:
DSSTox Substance ID:DTXSID401244203

Synonyms:113092-93-6;3-Chloro-3,4-dihydro-3-phenyl-2(1H)-quinolinone;DTXSID401244203

Suppliers and Price of 3-Chloro-3,4-dihydro-3-phenyl-2(1H)-quinolinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 3-Chloro-3,4-dihydro-3-phenyl-2(1H)-quinolinone

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:257.0607417
Heavy Atom Count:18
Complexity:327

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2=CC=CC=C2NC(=O)C1(C3=CC=CC=C3)Cl

Technology Process of 3-Chloro-3,4-dihydro-3-phenyl-2(1H)-quinolinone

There total 2 articles about 3-Chloro-3,4-dihydro-3-phenyl-2(1H)-quinolinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 6.0%

: 1022-66-8
3-phenyl-1,2,3,4-tetrahydro-2-quinolone

: 38035-81-3
3-phenyl-1H-quinolin-2-one

: 2859-30-5
2-chloro-3-phenyl-quinoline

: 113092-93-6
3-Chloro-3-phenyl-3,4-dihydro-1H-quinolin-2-one

Guidance literature:: With phosphorus pentachloride; In benzene; for 4h; Heating;
DOI:10.1248/cpb.35.2819

Reference yield:

: 19319-35-8
(E)-2-phenyl-3-(2-nitrophenyl)propenoic acid

: 113092-93-6
3-Chloro-3-phenyl-3,4-dihydro-1H-quinolin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / hydrogen / 5percent Pd-C / methanol / 6 h / Ambient temperature

2: 6 percent / PCl₅ / benzene / 4 h / Heating

With phosphorus pentachloride; hydrogen; palladium on activated charcoal; In methanol; benzene;
DOI:10.1248/cpb.35.2819