1-Keto Ketorolac

Base Information

Chemical Name:1-Keto Ketorolac
CAS No.:113502-52-6
Molecular Formula:C14H11NO2
Molecular Weight:225.24300
Hs Code.:2933998350
Mol file:113502-52-6.mol

Synonyms:5-Benzoyl-2,3-dihydro-1H-pyrrolizin-1-one;1-Keto Ketorolac;1H-Pyrrolizin-1-one,5-benzoyl-2,3-dihydro;

Suppliers and Price of 1-Keto Ketorolac

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-KetoKetorolac
10mg
$ 90.00

Total 13 raw suppliers

Chemical Property of 1-Keto Ketorolac

Chemical Property:

Boiling Point:427.9±33.0 °C(Predicted)
PKA:-11.95±0.20(Predicted)
PSA：39.07000
Density:1.26±0.1 g/cm3(Predicted)
LogP:2.30550

Purity/Quality:

99%, ^*data from raw suppliers

1-KetoKetorolac ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Ketorolac impurity.

Technology Process of 1-Keto Ketorolac

There total 3 articles about 1-Keto Ketorolac which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 74103-06-3
Ketorolac

: 113502-52-6
5-benzoyl-2,3-dihydro-1H-pyrrolizin-1-one

Guidance literature:: With iron(III) chloride; oxygen; In N,N-dimethyl-formamide; at 110 ℃; for 12h; Temperature; Solvent; Reagent/catalyst; Catalytic behavior; Mechanism;
DOI:10.1039/d0ob01790f

Reference yield: 66.0%

: C₁₅H₁₅NO₂

: 113502-52-6
5-benzoyl-2,3-dihydro-1H-pyrrolizin-1-one

Guidance literature:: With iron(III) chloride; oxygen; In N,N-dimethyl-formamide; at 110 ℃; for 17h;
DOI:10.1039/d0ob01790f

Reference yield:

: 74103-06-3
Ketorolac

: 77-86-1
2-amino-2-hydroxymethyl-1,3-propanediol

: (2,3-dihydro-1H-pyrrolizin-5-yl)(phenyl)methanone

: 113502-52-6
5-benzoyl-2,3-dihydro-1H-pyrrolizin-1-one

: 154476-25-2
(1-hydroxy-2,3-dihydro-1H-pyrrolizin-5-yl)(phenyl)methanone

: 167105-80-8
5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid (2-hydroxy-1,1-bis-hydroxymethyl-ethyl)-amide

Guidance literature:: With water; at 50 ℃; for 2160h; Product distribution; also as calcium salt, tromethamine salt or in the presence propyl gallate, BHT, EDTA and other additives; other time;
DOI:10.1002/jps.2600841003