Diethyl 1-(3,4-dimethoxyphenyl)hydrazine-1,2-dicarboxylate

Base Information

• Chemical Name: Diethyl 1-(3,4-dimethoxyphenyl)hydrazine-1,2-dicarboxylate
• CAS No.: 115171-05-6
• Molecular Formula: C14H20N2O6
• Molecular Weight: 312.323
• DSSTox Substance ID: DTXSID10573750
• Nikkaji Number: J1.694.065H
• Wikidata: Q82462564
• Mol file: 115171-05-6.mol

Synonyms:115171-05-6;SCHEMBL10562771;DTXSID10573750;ZVZRAPXGLVQUQL-UHFFFAOYSA-N;Diethyl 1-(3,4-dimethoxyphenyl)hydrazine-1,2-dicarboxylate;N,N'-bis(ethoxycarbonyl)-3,4-dimethoxyphenylhydrazine

Chemical Property of Diethyl 1-(3,4-dimethoxyphenyl)hydrazine-1,2-dicarboxylate

Chemical Property:

• XLogP3: 2.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 7
• Exact Mass: 312.13213636
• Heavy Atom Count: 22
• Complexity: 365

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)NN(C1=CC(=C(C=C1)OC)OC)C(=O)OCC

Technology Process of Diethyl 1-(3,4-dimethoxyphenyl)hydrazine-1,2-dicarboxylate

There total 2 articles about Diethyl 1-(3,4-dimethoxyphenyl)hydrazine-1,2-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

3,4-dimethoxyphenylmagnesium bromide (89980-69-8) + diethylazodicarboxylate (1972-28-7,218603-74-8) → N,N'-bis(ethoxycarbonyl)-3,4-dimethoxyphenylhydrazine (115171-05-6)

Guidance literature:

With magnesium; acetic acid; In tetrahydrofuran;

Reference yield: 88.0%

1,2-dimethoxybenzene (91-16-7) + diethylazodicarboxylate (1972-28-7,218603-74-8) → N,N'-bis(ethoxycarbonyl)-3,4-dimethoxyphenylhydrazine (115171-05-6)

Guidance literature:

With indium(III) chloride; for 0.05h; microwave irradiation;

DOI:10.1055/s-2001-18075

Reference yield: 12.0%

N,N'-bis(ethoxycarbonyl)-3,4-dimethoxyphenylhydrazine (115171-05-6) → 3,4-dimethoxyphenyl hydrazine (63756-98-9)

Guidance literature:

With potassium hydroxide; In isopropyl alcohol;

DOI:10.1016/S0040-4039(00)96662-0

upstream raw materials:

1,2-dimethoxybenzene

diethylazodicarboxylate

3,4-dimethoxyphenylmagnesium bromide

Downstream raw materials:

3,4-dimethoxyphenyl hydrazine