N-Methoxy-N-methyl-2-(trifluoromethyl)benzamide

Base Information

Chemical Name:N-Methoxy-N-methyl-2-(trifluoromethyl)benzamide
CAS No.:116332-63-9
Molecular Formula:C10H10F3NO2
Molecular Weight:233.19
Hs Code.:
DSSTox Substance ID:DTXSID30555391
Nikkaji Number:J2.379.650C
Wikidata:Q82436720
Mol file:116332-63-9.mol

Synonyms:N-Methoxy-N-methyl-2-(trifluoromethyl)benzamide;116332-63-9;Benzamide, N-methoxy-N-methyl-2-(trifluoromethyl)-;SCHEMBL8575500;DTXSID30555391;RFCOFRJQQLVIGL-UHFFFAOYSA-N;AKOS008716771;C77776

Suppliers and Price of N-Methoxy-N-methyl-2-(trifluoromethyl)benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Acrotein
N-Methoxy-N-methyl-2-(trifluoromethyl)benzamide 97%
5g
$ 302.50

Total 3 raw suppliers

Chemical Property of N-Methoxy-N-methyl-2-(trifluoromethyl)benzamide

Chemical Property:

PSA：29.54000
LogP:2.33880
XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:233.06636305
Heavy Atom Count:16
Complexity:255

Purity/Quality:

99.90% ^*data from raw suppliers

N-Methoxy-N-methyl-2-(trifluoromethyl)benzamide 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C(=O)C1=CC=CC=C1C(F)(F)F)OC

Technology Process of N-Methoxy-N-methyl-2-(trifluoromethyl)benzamide

There total 2 articles about N-Methoxy-N-methyl-2-(trifluoromethyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 201230-82-2
carbon monoxide

: 392-83-6
o-trifluoromethylphenyl bromide

: 6638-79-5
N,O-dimethylhydroxylamine*hydrochloride

: 116332-63-9
N‐methoxy‐N‐methyl‐2‐(trifluoromethyl)benzamide

Guidance literature:: With potassium phosphate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; palladium diacetate; In m-xylene; at 110 ℃; for 20h; under 760 Torr;
DOI:10.1021/ol061902t

Reference yield: 82.0%

: 6638-79-5
N,O-dimethylhydroxylamine*hydrochloride

: 433-97-6
2-trifluoromethylbenzoic acid

: 116332-63-9
N‐methoxy‐N‐methyl‐2‐(trifluoromethyl)benzamide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 20 ℃; for 16h;

Reference yield: 87.0%

: 2373-51-5
chloro-methylsulfanyl-methane

: 116332-63-9
N‐methoxy‐N‐methyl‐2‐(trifluoromethyl)benzamide

: 2‐(methylsulfanyl)‐1‐[2‐(trifluoromethyl)phenyl]ethanone

Guidance literature:: With 4,4'-di-tert-butylbiphenyl; lithium; In tetrahydrofuran; at -78 ℃; for 3h; chemoselective reaction; Schlenk technique; Inert atmosphere;
DOI:10.1002/ejoc.201800095