Diethyl [benzamido(phenyl)methyl]phosphonate

Base Information

Chemical Name:Diethyl [benzamido(phenyl)methyl]phosphonate
CAS No.:123978-87-0
Molecular Formula:C18H22NO4P
Molecular Weight:347.351
Hs Code.:
ChEMBL ID:CHEMBL2228020
DSSTox Substance ID:DTXSID60558234
Nikkaji Number:J2.630.065G
Mol file:123978-87-0.mol

Synonyms:123978-87-0;Diethyl [benzamido(phenyl)methyl]phosphonate;CHEMBL2228020;WSFJEDKBRTZTPH-UHFFFAOYSA-;DTXSID60558234;diethyl a-benzamidobenzylphosphonate;DIETHYL BENZAMIDO(PHENYL)METHYLPHOSPHONATE;InChI=1/C18H22NO4P/c1-3-22-24(21,23-4-2)18(16-13-9-6-10-14-16)19-17(20)15-11-7-5-8-12-15/h5-14,18H,3-4H2,1-2H3,(H,19,20)

Suppliers and Price of Diethyl [benzamido(phenyl)methyl]phosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Diethyl [benzamido(phenyl)methyl]phosphonate

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:347.12864518
Heavy Atom Count:24
Complexity:421

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOP(=O)(C(C1=CC=CC=C1)NC(=O)C2=CC=CC=C2)OCC

Technology Process of Diethyl [benzamido(phenyl)methyl]phosphonate

There total 4 articles about Diethyl [benzamido(phenyl)methyl]phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 591-50-4
iodobenzene

: 201230-82-2
carbon monoxide

: 16814-08-7,42077-95-2,42077-97-4
diethyl 1-aminophenylmethylphosphonate

: 1062573-06-1
diethyl N-phenylglyoxyloyl-α-aminobenzyl-phosphonate

: 123978-87-0
diethyl N-benzoyl-α-aminobenzyl-phosphonate

Guidance literature:: With triethylamine; triphenylphosphine; palladium diacetate; In N,N-dimethyl-formamide; at 50 ℃; for 40h; under 30003 Torr;
DOI:10.1016/j.tet.2008.06.096

Reference yield: 69.0%

: 16656-50-1
diethyl 1-amino-1-phenylmethylphosphonate hydrochloride

: 98-88-4
benzoyl chloride

: 123978-87-0
diethyl N-benzoyl-α-aminobenzyl-phosphonate

Guidance literature:: With triethylamine; In N,N-dimethyl-formamide; for 1h; Ambient temperature;
DOI:10.1016/0968-0896(96)00186-1

Reference yield:

: 108183-32-0
diethyl α-bromo-α-(benzoylamino)methylphosphonate

: 591-51-5
phenyllithium

: 123978-87-0
diethyl N-benzoyl-α-aminobenzyl-phosphonate

Guidance literature:: With LiCu; Yield given. Multistep reaction; 1.) THF, 0 deg C, 10 min, 2.) -78 deg C to room temp., 12 h;
DOI:10.1055/s-1989-27162