Oxiranecarboxylic acid, 2-[6-(4-chlorophenoxy)hexyl]-, (R)-

Base Information

Chemical Name:Oxiranecarboxylic acid, 2-[6-(4-chlorophenoxy)hexyl]-, (R)-
CAS No.:124083-14-3
Molecular Formula:C15H19ClO4
Molecular Weight:298.766
Hs Code.:
UNII:5HH4PR8XLD
Wikidata:Q76403946
Mol file:124083-14-3.mol

Synonyms:124083-14-3;Etomoxir free acid;5HH4PR8XLD;Oxiranecarboxylic acid, 2-[6-(4-chlorophenoxy)hexyl]-, (R)-;(2R)-2-(6-(4-Chlorophenoxy)hexyl)oxirane-2-carboxylic acid;(2R)-2-[6-(4-chlorophenoxy)hexyl]oxirane-2-carboxylic acid;(R)-2-(6-(4-Chlorophenoxy)hexyl)oxirane-2-carboxylic acid;Oxiranecarboxylic acid, 2-(6-(4-chlorophenoxy)hexyl)-, (R)-;UNII-5HH4PR8XLD;SCHEMBL10436373;SB75312;Oxiranecarboxylic acid,2-[6-(4-chlorophenoxy)hexyl]-,(R)-

Suppliers and Price of Oxiranecarboxylic acid, 2-[6-(4-chlorophenoxy)hexyl]-, (R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Oxiranecarboxylic acid, 2-[6-(4-chlorophenoxy)hexyl]-, (R)-

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:9
Exact Mass:298.0971868
Heavy Atom Count:20
Complexity:315

Purity/Quality:: ≥95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C(O1)(CCCCCCOC2=CC=C(C=C2)Cl)C(=O)O
Isomeric SMILES:C1[C@](O1)(CCCCCCOC2=CC=C(C=C2)Cl)C(=O)O

Technology Process of Oxiranecarboxylic acid, 2-[6-(4-chlorophenoxy)hexyl]-, (R)-

There total 7 articles about Oxiranecarboxylic acid, 2-[6-(4-chlorophenoxy)hexyl]-, (R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 124083-20-1,828934-40-3
(R)-(+)-etomoxir

: 124083-14-3
etomoxir

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; Ambient temperature;
DOI:10.1016/S0040-4039(01)80643-2

Reference yield: 20.0%

: 124083-18-7
{(S)-2-[6-(4-Chloro-phenoxy)-hexyl]-oxiranyl}-methanol

: 7170-57-2
7-(4-chlorophenoxy)heptanoic acid

: 124083-14-3
etomoxir

Guidance literature:: With sodium periodate; ruthenium trichloride;
DOI:10.1016/S0040-4039(01)80643-2

Reference yield:

: 82258-37-5
ethyl 2-[6-(p-chlorophenoxy)hexyl]acrylate

: 124083-14-3
etomoxir

Guidance literature:: Multi-step reaction with 4 steps

1: aluminium trihydride / diethyl ether

2: 49 percent / t-butylhydroperoxide, titanium isopropoxide, diethyl L-(+)-tartrate / -20 deg C, 3 h. then room temp., 1 h.

3: 1.) NaIO₄; 2.) NaHCO₃ / 1.) RuCl₃ / 1.) CCl₄, CH₃CN, H₂O, room temp., 7 h.; 2.) DMF, room temp.

4: 71 percent / NaOH / tetrahydrofuran / Ambient temperature

With aluminium hydride; titanium(IV) isopropylate; tert.-butylhydroperoxide; sodium hydroxide; sodium periodate; diethyl (2R,3R)-tartrate; sodium hydrogencarbonate; ruthenium trichloride; In tetrahydrofuran; diethyl ether;
DOI:10.1016/S0040-4039(01)80643-2