1H-Pyrrole-2-carboxylic acid, 4-methyl-3-phenyl-, ethyl ester

Base Information

Chemical Name:1H-Pyrrole-2-carboxylic acid, 4-methyl-3-phenyl-, ethyl ester
CAS No.:124901-12-8
Molecular Formula:C14H15NO2
Molecular Weight:229.279
Hs Code.:
DSSTox Substance ID:DTXSID60443772
Nikkaji Number:J3.196.010J
Wikidata:Q82261718
Mol file:124901-12-8.mol

Synonyms:124901-12-8;Ethyl 4-methyl-3-phenyl-1H-pyrrole-2-carboxylate;1H-Pyrrole-2-carboxylic acid, 4-methyl-3-phenyl-, ethyl ester;SCHEMBL1126789;DTXSID60443772;ZXBOCLDHYGJYDU-UHFFFAOYSA-N;ethyl 4-methyl-3-phenyl-1h-pyrrole-2-carboxy-late;3-Phenyl-4-methyl-1H-pyrrole-2-carboxylic acid ethyl ester;4-methyl-3-phenyl-1H-pyrrole-2-carboxylic acid ethyl ester

Suppliers and Price of 1H-Pyrrole-2-carboxylic acid, 4-methyl-3-phenyl-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 1H-Pyrrole-2-carboxylic acid, 4-methyl-3-phenyl-, ethyl ester

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:229.110278721
Heavy Atom Count:17
Complexity:261

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(C(=CN1)C)C2=CC=CC=C2

Technology Process of 1H-Pyrrole-2-carboxylic acid, 4-methyl-3-phenyl-, ethyl ester

There total 8 articles about 1H-Pyrrole-2-carboxylic acid, 4-methyl-3-phenyl-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 705-60-2,18315-84-9,58321-79-2
1-phenyl-2-nitroprop-1-ene

: 2999-46-4
Ethyl isocyanoacetate

: 124901-12-8
ethyl 4-methyl-3-phenyl-1H-pyrrole-2-carboxylate

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; isopropyl alcohol; at 20 ℃; for 3h;
DOI:10.1134/S1070428007020236

Reference yield: 90.0%

: 705-60-2
(2-nitroprop-1-enyl)benzene

: 2999-46-4
Ethyl isocyanoacetate

: 124901-12-8
ethyl 4-methyl-3-phenyl-1H-pyrrole-2-carboxylate

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; isopropyl alcohol; at 10 - 20 ℃;

Reference yield:

: 100-52-7
benzaldehyde

: 124901-12-8
ethyl 4-methyl-3-phenyl-1H-pyrrole-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: ammonium acetate; acetic acid / 5 h / Reflux

2: potassium carbonate / tetrahydrofuran / 16 h / 20 °C

With ammonium acetate; potassium carbonate; acetic acid; In tetrahydrofuran;