4-(1,4-Dioxaspiro[4.5]decan-8-yl)morpholine

Base Information

Chemical Name:4-(1,4-Dioxaspiro[4.5]decan-8-yl)morpholine
CAS No.:127562-53-2
Molecular Formula:C12H21NO3
Molecular Weight:227.304
Hs Code.:2934999090
DSSTox Substance ID:DTXSID00704894
Wikidata:Q82637464
Mol file:127562-53-2.mol

Synonyms:4-(1,4-dioxaspiro[4.5]decan-8-yl)morpholine;127562-53-2;4-(1,4-Dioxaspiro[4.5]dec-8-yl)morpholine;SCHEMBL1800548;DTXSID00704894;JDGLFTXYDPTSQZ-UHFFFAOYSA-N;CFA56253;AKOS016014238;AC-9411;BS-20562;CS-0210440;FT-0715582;4-(1,4-Dioxa-spiro[4.5]dec-8-yl)-morpholine;A850004;J-513205

Suppliers and Price of 4-(1,4-Dioxaspiro[4.5]decan-8-yl)morpholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(1,4-Dioxaspiro[4.5]dec-8-yl)morpholine
25g
$ 1320.00

Crysdot
4-(1,4-Dioxaspiro[4.5]decan-8-yl)morpholine 95+%
5g
$ 790.00

Chemenu
4-(1,4-dioxaspiro[4.5]decan-8-yl)morpholine 95%
5g
$ 746.00

American Custom Chemicals Corporation
4-(1,4-DIOXASPIRO[4.5]DECAN-8-YL)MORPHOLINE 95.00%
5MG
$ 497.62

Alichem
4-(1,4-Dioxaspiro[4.5]decan-8-yl)morpholine
5g
$ 821.94

AK Scientific
4-(1,4-Dioxaspiro[4.5]decan-8-yl)morpholine
5g
$ 1171.00

AK Scientific
4-(1,4-Dioxaspiro[4.5]decan-8-yl)morpholine
250mg
$ 184.00

Total 20 raw suppliers

Chemical Property of 4-(1,4-Dioxaspiro[4.5]decan-8-yl)morpholine

Chemical Property:

PSA：30.93000
LogP:0.94220
Storage Temp.:2-8°C
XLogP3:0.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:227.15214353
Heavy Atom Count:16
Complexity:224

Purity/Quality:

97% ^*data from raw suppliers

4-(1,4-Dioxaspiro[4.5]dec-8-yl)morpholine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2(CCC1N3CCOCC3)OCCO2
Uses 4-(1,4-Dioxaspiro[4.5]dec-8-yl)morpholine is an intermediate in the synthesis of 4-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)cyclohex-3-en-1-yl]morpholine (T3026350), a reactant used in the preparation of azaindole derivatives as c-Jun N-terminal kinase inhibitors.

Technology Process of 4-(1,4-Dioxaspiro[4.5]decan-8-yl)morpholine

There total 1 articles about 4-(1,4-Dioxaspiro[4.5]decan-8-yl)morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 110-91-8,99108-56-2
morpholine

: 4746-97-8
cyclohexanedione monoethylene ketal

: 127562-53-2
4-(1,4-dioxaspiro<4.5>dec-8-yl)morpholine

Guidance literature:: With sodium cyanoborohydride; acetic acid; In dichloromethane; at 25 ℃;

Reference yield: 99.1%

: 109-01-3
1-methyl-piperazine

: 127562-53-2
4-(1,4-dioxaspiro<4.5>dec-8-yl)morpholine

: 155778-83-9
4-(1,4-dioxaspiro<4,5>dec-8-yl)-1-methylpiperazine

Guidance literature:: 1-methyl-piperazine; 4-(1,4-dioxaspiro<4.5>dec-8-yl)morpholine; With sodium tris(acetoxy)borohydride; acetic acid; In 1,2-dichloro-ethane; at 3 - 20 ℃;

With sodium hydroxide; water; In 1,2-dichloro-ethane; for 0.916667h;

Reference yield: 87.0%

: 127562-53-2
4-(1,4-dioxaspiro<4.5>dec-8-yl)morpholine

: 139025-93-7
4-(morpholin-4-yl)cyclohexan-1-one

Guidance literature:: 4-(1,4-dioxaspiro<4.5>dec-8-yl)morpholine; With hydrogenchloride; water; In tetrahydrofuran; for 17h;

With water; sodium hydrogencarbonate; In tetrahydrofuran;