4-morpholinocyclohex-1-enyl trifluoromethanesulfonate

Base Information

Chemical Name:4-morpholinocyclohex-1-enyl trifluoromethanesulfonate
CAS No.:1046793-55-8
Molecular Formula:C11H16F3NO4S
Molecular Weight:315.314
Hs Code.:2934999090
Mol file:1046793-55-8.mol

Synonyms:4-morpholinocyclohex-1-enyl trifluoromethanesulfonate

Suppliers and Price of 4-morpholinocyclohex-1-enyl trifluoromethanesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-?Morpholinocyclohex-?1-?en-?1-?ylTrifluoromethanesulf?onate
500mg
$ 735.00

Total 5 raw suppliers

Chemical Property of 4-morpholinocyclohex-1-enyl trifluoromethanesulfonate

Chemical Property:

PSA：64.22000
LogP:2.63990

Purity/Quality:

98%min ^*data from raw suppliers

4-?Morpholinocyclohex-?1-?en-?1-?ylTrifluoromethanesulf?onate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 4-?Morpholinocyclohex-?1-?en-?1-?yl Trifluoromethanesulf?onate is a reagent used in the preparation of inhibitors of c-Jun N-terminal kinase in the treatment of neurodegenerative disorders and autoimmune diseases.

Technology Process of 4-morpholinocyclohex-1-enyl trifluoromethanesulfonate

There total 3 articles about 4-morpholinocyclohex-1-enyl trifluoromethanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 37595-74-7
N,N-phenylbistrifluoromethane-sulfonimide

: 139025-93-7
4-(morpholin-4-yl)cyclohexan-1-one

: 1046793-55-8
4-morpholinocyclohex-1-en-1-yl trifluoromethanesulfonate

Guidance literature:: 4-(morpholin-4-yl)cyclohexan-1-one; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 1h;

N,N-phenylbistrifluoromethane-sulfonimide; In tetrahydrofuran; at -78 - 20 ℃; for 20.5h;

Reference yield:

: 4746-97-8
cyclohexanedione monoethylene ketal

: 1046793-55-8
4-morpholinocyclohex-1-en-1-yl trifluoromethanesulfonate

Guidance literature:: Multi-step reaction with 3 steps

1: acetic acid; sodium cyanoborohydride / dichloromethane / 25 °C

2: hydrogenchloride / water; tetrahydrofuran / 21 h / 25 - 80 °C

3: lithium hexamethyldisilazane / tetrahydrofuran / -78 - 25 °C

With hydrogenchloride; sodium cyanoborohydride; acetic acid; lithium hexamethyldisilazane; In tetrahydrofuran; dichloromethane; water;

Reference yield:

: 127562-53-2
4-(1,4-dioxaspiro<4.5>dec-8-yl)morpholine

: 1046793-55-8
4-morpholinocyclohex-1-en-1-yl trifluoromethanesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / water; tetrahydrofuran / 21 h / 25 - 80 °C

2: lithium hexamethyldisilazane / tetrahydrofuran / -78 - 25 °C

With hydrogenchloride; lithium hexamethyldisilazane; In tetrahydrofuran; water;