tert-Butyl 2-methylhydrazinecarboxylate

Base Information

Chemical Name:tert-Butyl 2-methylhydrazinecarboxylate
CAS No.:127799-54-6
Molecular Formula:C6H14N2O2
Molecular Weight:146.189
Hs Code.:2928009090
European Community (EC) Number:819-787-4
DSSTox Substance ID:DTXSID00576659
Nikkaji Number:J1.286.463I
Wikidata:Q72491244
Mol file:127799-54-6.mol

Synonyms:tert-Butyl 2-methylhydrazinecarboxylate;127799-54-6;1-N-Boc-2-methylhydrazine;Hydrazinecarboxylic acid, 2-methyl-, 1,1-dimethylethyl ester;1-Boc-2-methylhydrazine;tert-butyl N-(methylamino)carbamate;N'-methyl(tert-butoxy)carbohydrazide;1-(T-BUTYLOXY)CARBONYL-2-METHYLHYDRAZINE;2-Methylhydrazinecarboxylic acid tert-butyl ester;MFCD16660139;tert-butyl 2-methylhydrazine-1-carboxylate;SCHEMBL289320;DTXSID00576659;UZRUVUYVHGPEAP-UHFFFAOYSA-N;BCP14206;FD1328;tert-Butyl2-methylhydrazinecarboxylate;AKOS016003285;CS-W019664;N-(t-Butoxycarbonyl)-N'-methylhydrazine;N-tert-butoxycarbonyl-N'-methylhydrazine;AS-10335;SY024141;EN300-227419;2-Methyl-2-propanyl 2-methylhydrazinecarboxylate;A889146;1-[(1,1-Dimethylethoxy)carbonyl]-2-methylhydrazine

Suppliers and Price of tert-Butyl 2-methylhydrazinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
tert-Butyl2-methylhydrazinecarboxylate
500mg
$ 220.00

Oakwood
tert-Butyl2-methylhydrazinecarboxylate 95%
250mg
$ 101.00

Oakwood
tert-Butyl2-methylhydrazinecarboxylate 95%
100mg
$ 50.00

Crysdot
tert-Butyl2-methylhydrazinecarboxylate 98%
5g
$ 386.00

Crysdot
tert-Butyl2-methylhydrazinecarboxylate 98%
10g
$ 644.00

Crysdot
tert-Butyl2-methylhydrazinecarboxylate 98%
25g
$ 1208.00

Ark Pharm
tert-Butyl2-methylhydrazinecarboxylate 98%
250mg
$ 22.00

Ark Pharm
tert-Butyl2-methylhydrazinecarboxylate 98%
5g
$ 165.00

American Custom Chemicals Corporation
TERT-BUTYL-2-METHYLHYDRAZINECARBOXYLATE 95.00%
5MG
$ 505.62

Ambeed
tert-Butyl2-methylhydrazinecarboxylate 98%
5g
$ 173.00

Total 39 raw suppliers

Chemical Property of tert-Butyl 2-methylhydrazinecarboxylate

Chemical Property:

Melting Point:49-51℃
PKA:10.73±0.43(Predicted)
Density:0.982±0.06 g/cm3 (20 oC 760 Torr)
Storage Temp.:Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
XLogP3:0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:146.105527694
Heavy Atom Count:10
Complexity:117

Purity/Quality:

99%, ^*data from raw suppliers

tert-Butyl2-methylhydrazinecarboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NNC

Technology Process of tert-Butyl 2-methylhydrazinecarboxylate

There total 5 articles about tert-Butyl 2-methylhydrazinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 127799-53-5
1-[(1,1-dimethylethoxy)carbonyl]-2-[(phenylmethoxy)carbonyl]-2-methylhydrazine

: 127799-54-6
2-Methylhydrazinecarboxylic acid,1,1-dimethylethyl ester

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; for 12h;

Reference yield: 83.0%

: 356534-53-7
t-butyl carbazate triphenylphosphine bromide

: 74-88-4
methyl iodide

: 127799-54-6
2-Methylhydrazinecarboxylic acid,1,1-dimethylethyl ester

Guidance literature:: t-butyl carbazate triphenylphosphine bromide; With n-butyllithium; In tetrahydrofuran; hexane; for 1h; cooling;

methyl iodide; In tetrahydrofuran; hexane; for 5h;

With sodium hydroxide; In dichloromethane; at 20 ℃; for 0.5h;
DOI:10.1021/ja039643f

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 127799-54-6
2-Methylhydrazinecarboxylic acid,1,1-dimethylethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: 78.1 percent / hydrazine monohydrate / propan-2-ol / 0.33 h / 20 °C

2.1: 64 percent / toluene / 6 h

3.1: n-BuLi / tetrahydrofuran; hexane / 1 h / cooling

3.2: tetrahydrofuran; hexane / 5 h

3.3: 83 percent / aq. NaOH / CH₂Cl₂ / 0.5 h / 20 °C

With n-butyllithium; hydrazine hydrate; In tetrahydrofuran; hexane; isopropyl alcohol; toluene;
DOI:10.1021/ja039643f