3-Bromo-N-Methoxy-N-Methyl-Propionamide

Base Information

• Chemical Name: 3-Bromo-N-Methoxy-N-Methyl-Propionamide
• CAS No.: 128562-58-3
• Molecular Formula: C5H10BrNO2
• Molecular Weight: 196.044
• Mol file: 128562-58-3.mol

Synonyms:N-methoxy-N-methyl-3-bromopropionamide;3-bromo-N-methoxy-N-methylpropanamide;3-bromo-N-methoxy-N-methyl-propionamide;N,O-dimethyl-3-bromopropanamide;N-methyl-N-methoxy-3-bromopropionamide;

Chemical Property of 3-Bromo-N-Methoxy-N-Methyl-Propionamide

Chemical Property:

• Boiling Point: 187.5±42.0 °C(Predicted)
• PSA: 29.54000
• Density: 1.452±0.06 g/cm3(Predicted)
• LogP: 0.79120

Purity/Quality:

99% ^*data from raw suppliers

3-bromo-N-methoxy-N-methylpropanamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Bromo-N-Methoxy-N-Methyl-Propionamide

There total 4 articles about 3-Bromo-N-Methoxy-N-Methyl-Propionamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

N,O-dimethylhydroxylamine*hydrochloride (6638-79-5) + 3-Bromopropionyl chloride (15486-96-1) → N-methyl-N-methoxy-3-bromopropionamide (128562-58-3)

Guidance literature:

With pyridine; In dichloromethane; at 0 - 20 ℃; for 72h;

Reference yield: 78.0%

3-Bromopropionic acid (590-92-1) + N,O-dimethylhydroxylamine*hydrochloride (6638-79-5) → N-methyl-N-methoxy-3-bromopropionamide (128562-58-3)

Guidance literature:

With pyridine; carbon tetrabromide; triphenylphosphine; In dichloromethane; for 0.166667h; Ambient temperature;

Reference yield:

3-Bromopropionyl chloride (15486-96-1) + N,0-dimethylhydroxylamine (1117-97-1) → N-methyl-N-methoxy-3-bromopropionamide (128562-58-3)

Guidance literature:

DOI:10.1016/S0040-4039(01)93926-7 DOI:10.1016/0040-4039(95)01251-C

upstream raw materials:

3-Bromopropionic acid

N,O-dimethylhydroxylamine*hydrochloride

3-Bromopropionyl chloride

N,0-dimethylhydroxylamine

Downstream raw materials:

2-benzenesulfonyl-pentanedioic acid bis-(methoxy-methyl-amide)

N-methylheptanamide

4-cyano-4-(4-methylphenyl)-4-morpholino-N-methoxy-N-methylbutyramide

4-(3-chlorophenyl)-4-cyano-4-morpholino-N-methoxy-N-methylbutyramide