Ethanone, 1-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxyphenyl]-

Base Information

Chemical Name:Ethanone, 1-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxyphenyl]-
CAS No.:132255-78-8
Molecular Formula:C15H24O3Si
Molecular Weight:280.439
Hs Code.:
DSSTox Substance ID:DTXSID00459559
Nikkaji Number:J834.990H
Wikidata:Q82283355

Synonyms:132255-78-8;Ethanone, 1-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxyphenyl]-;SCHEMBL336061;Acetovanillone, TBDMS derivative;DTXSID00459559;EN300-22905450;1-(4-t-butyldimethylsilyloxy-3-methoxyphenyl)ethanone;3'-Methoxy-4'-(tert-butyldimethylsiloxy)acetophenone;1-(4-((tert-Butyldimethylsilyl)oxy)-3-methoxyphenyl)ethanone;1-[4-(t-butyl-dimethyl-silanyloxy)-3-methoxy-phenyl]-ethanone;1-{4-[(tert-butyldimethylsilyl)oxy]-3-methoxyphenyl}ethan-1-one;4'-Hydroxy-3'-methoxyacetophenone, tert-butyldimethylsilyl ether

Suppliers and Price of Ethanone, 1-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxyphenyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Ethanone, 1-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxyphenyl]-

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:280.14947116
Heavy Atom Count:19
Complexity:320

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=CC(=C(C=C1)O[Si](C)(C)C(C)(C)C)OC

Technology Process of Ethanone, 1-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxyphenyl]-

There total 5 articles about Ethanone, 1-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxyphenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 18162-48-6
tert-butyldimethylsilyl chloride

: 498-02-2
1-(3-methoxy-4-hydroxyphenyl)ethanone

: 132255-78-8
4-(tert.-Butyldimethylsilyloxy)-3-methoxyacetophenon

Guidance literature:: With 1H-imidazole; In N,N-dimethyl-formamide; for 3h; Ambient temperature;
DOI:10.1002/ardp.19903231208

Reference yield: 79.2%

: 288-32-4
1H-imidazole

: 18162-48-6
tert-butyldimethylsilyl chloride

: 498-02-2
1-(3-methoxy-4-hydroxyphenyl)ethanone

: 132255-78-8
4-(tert.-Butyldimethylsilyloxy)-3-methoxyacetophenon

Guidance literature:: In tetrahydrofuran;

Reference yield:

: 121-33-5,8014-42-4
vanillin

: 132255-78-8
4-(tert.-Butyldimethylsilyloxy)-3-methoxyacetophenon

Guidance literature:: Multi-step reaction with 2 steps

1: imidazole / dimethylformamide / 12 h / Ambient temperature

2: 1.) Mg, 2.) N-chlorosuccinimide / 1.) C₆H₆, THF, 10 min, 2.) C₆H₆, THF, a) 0 deg C, 5 min, b) RT, 25 min

With 1H-imidazole; N-chloro-succinimide; magnesium; In N,N-dimethyl-formamide;
DOI:10.1002/jccs.199700010