Silane, (2,6-difluorophenyl)trimethyl-

Base Information

• Chemical Name: Silane, (2,6-difluorophenyl)trimethyl-
• CAS No.: 133117-48-3
• Molecular Formula: C9H12F2Si
• Molecular Weight: 186.277
• Mol file: 133117-48-3.mol

Synonyms:.2,6-Difluorophenyltrimethylsilane;(2,6-difluorophenyl)trimethylsilane;.2,6-Difluorphenyl-trimethylsilan;.2,6-difluorophenyl-trimethylsilane;

Chemical Property of Silane, (2,6-difluorophenyl)trimethyl-

Chemical Property:

• PSA: 0.00000
• LogP: 2.51000

Purity/Quality:

More than 98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Silane, (2,6-difluorophenyl)trimethyl-

There total 3 articles about Silane, (2,6-difluorophenyl)trimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

chloro-trimethyl-silane (75-77-4) + 1,3-Difluorobenzene (372-18-9) → 1,3-difluoro-2-trimethylsilylbenzene (133117-48-3)

Guidance literature:

With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In tetrahydrofuran; hexane; at -75 - 20 ℃; for 19h;

DOI:10.1016/S0040-4020(01)80238-6

Reference yield:

1,3-Difluorobenzene (372-18-9) + ethenyltrimethylsilane (754-05-2) → 1,3-difluoro-2-trimethylsilylbenzene (133117-48-3)

Guidance literature:

With [ⁱPr₂Im]Ni(η²-H₂C=CHSiMe₃)₂; In toluene; at 120 ℃; for 36h; Sealed tube;

DOI:10.1021/jacs.7b05574

Reference yield:

1,3-Difluorobenzene (372-18-9) + (trifluoromethyl)trimethylsilane (81290-20-2) → 1,3-difluoro-2-trimethylsilylbenzene (133117-48-3)

Guidance literature:

With cesium fluoride; In 1,2-dimethoxyethane; at 0 ℃; for 1h; Reagent/catalyst; Solvent; Glovebox;

DOI:10.1021/acs.joc.7b01525

upstream raw materials:

chloro-trimethyl-silane

1,3-Difluorobenzene

ethenyltrimethylsilane

(trifluoromethyl)trimethylsilane

Downstream raw materials:

2,6-difluoroacetophenone

1-bromo-2,6-difluorobenzene

1,3-Difluorobenzene

2,6-difluoro-1-nitrobenzene