1-[(4-Fluorophenyl)methyl]-1H-indazole-3-carboxylic acid

Base Information

Chemical Name:1-[(4-Fluorophenyl)methyl]-1H-indazole-3-carboxylic acid
CAS No.:50264-63-6
Molecular Formula:C15H11FN2O2
Molecular Weight:270.263
Hs Code.:2933990090
Mol file:50264-63-6.mol

Synonyms:1H-Indazole-3-carboxylic acid,1-(p-fluorobenzyl);1-(4-fluoro-benzyl)-1H-indazole-3-carboxylic acid;

Suppliers and Price of 1-[(4-Fluorophenyl)methyl]-1H-indazole-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-[(4-Fluorophenyl)methyl]-1H-indazole-3-carboxylicAcid
50mg
$ 75.00

Matrix Scientific
1-[(4-Fluorophenyl)methyl]-1H-indazole-3-carboxylic acid >97%
1g
$ 487.00

Matrix Scientific
1-[(4-Fluorophenyl)methyl]-1H-indazole-3-carboxylic acid >97%
500mg
$ 390.00

Crysdot
1-(4-Fluorobenzyl)-1H-indazole-3-carboxylicacid 95+%
1g
$ 301.00

Chemtos
AB-FUBINACAmetabolite41mg/ml
1ml of 1 mg
$ 140.00

Chemenu
1-(4-Fluorobenzyl)-1H-indazole-3-carboxylicacid 95%
1g
$ 284.00

Cayman Chemical
AB-FUBINACA metabolite 4 ≥98%
5mg
$ 402.00

Cayman Chemical
AB-FUBINACA metabolite 4 ≥98%
1mg
$ 103.00

Apolloscientific
1-[(4-Fluorophenyl)methyl]-1H-indazole-3-carboxylicacid
1g
$ 214.00

Apolloscientific
1-[(4-Fluorophenyl)methyl]-1H-indazole-3-carboxylicacid
500mg
$ 160.00

Total 4 raw suppliers

Chemical Property of 1-[(4-Fluorophenyl)methyl]-1H-indazole-3-carboxylic acid

Chemical Property:

Vapor Pressure:1.24E-10mmHg at 25°C
Melting Point:194 °C(Solv: acetic acid (64-19-7))
Boiling Point:495.5°Cat760mmHg
PKA:3.06±0.10(Predicted)
Flash Point:253.4°C
PSA：55.12000
Density:1.34g/cm³
LogP:2.92190

Purity/Quality:

97% ^*data from raw suppliers

1-[(4-Fluorophenyl)methyl]-1H-indazole-3-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description AB-FUBINACA metabolite 4 (Item No. 20179) is an analytical reference standard that is structurally classified as a synthetic cannabinoid. It is the carboxylic acid indazole 4-fluorobenzyl metabolite of AB-FUBINACA (Item Nos. 14039 | ISO60211). The physiological and toxicological properties of 1-[(4-Fluorophenyl)methyl]-1H-indazole-3-carboxylic acid are not known. This product is intended for forensic and research applications.
Uses 1-[(4-Fluorophenyl)methyl]-1H-indazole-3-carboxylic Acid is used as a reactant in the preparaion of cannabinoid indole and indazole compounds for treating pain and nausea. Synthetic cannabinoids

Technology Process of 1-[(4-Fluorophenyl)methyl]-1H-indazole-3-carboxylic acid

There total 5 articles about 1-[(4-Fluorophenyl)methyl]-1H-indazole-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 459-46-1
4-Fluorobenzyl bromide

: 50264-63-6
1-(4-fluoro-benzyl)-1H-indazole-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium tert-butylate / tetrahydrofuran / 25 °C / Cooling with ice

1.2: 5 h / 0 - 20 °C

2.1: sodium hydroxide / methanol / 12 h / 18 - 25 °C

With potassium tert-butylate; sodium hydroxide; In tetrahydrofuran; methanol;

Reference yield:

: 942-24-5
3-methoxycarbonylindole

: 50264-63-6
1-(4-fluoro-benzyl)-1H-indazole-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium tert-butylate / tetrahydrofuran / 1 h / 0 - 20 °C / Inert atmosphere

1.2: 48 h / 0 °C

2.1: sodium hydroxide; water / methanol / 18 h / Reflux; Inert atmosphere

With potassium tert-butylate; water; sodium hydroxide; In tetrahydrofuran; methanol;
DOI:10.1021/acschemneuro.7b00267

Reference yield:

: 459-46-1
4-Fluorobenzyl bromide

: 43120-28-1
methyl 1H-indazole-3-carboxylate

: 50264-63-6
1-(4-fluoro-benzyl)-1H-indazole-3-carboxylic acid

Guidance literature:: 4-Fluorobenzyl bromide; methyl 1H-indazole-3-carboxylate; With potassium carbonate; In acetonitrile; at 60 ℃;

With water; sodium hydroxide; In 1,4-dioxane; at 50 ℃;